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Che-1 activates XIAP expression in response to DNA damage

X-linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis proteins family that selectively binds and inhibits caspase-3, -7 and -9. As such, XIAP is an extremely potent suppresso...

T Bruno, S Iezzi, F De Nicola, M Di Padova, A Desantis… in Cell Death & Differentiation (2008)