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    Article

    Novel Therapeutic Strategies in Adult Acute Lymphoblastic Leukemia – A Focus on Emerging Monoclonal Antibodies

    The outcomes in adult B-cell acute lymphoblastic leukemia (ALL) remain inferior to those achieved in pediatric populations. Targeted therapy with monoclonal antibodies may improve outcomes in adult B-cell ALL ...

    Naval Daver, Susan O’Brien in Current Hematologic Malignancy Reports (2013)

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    Article

    Role of Tyrosine Kinase Inhibitors in the Management of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

    The Philadelphia chromosome is the most common cytogenetic abnormality found in adult patients diagnosed with acute lymphoblastic leukemia. The result of this abnormality is the BCR-ABL protein, a constitutive...

    Michael S. Mathisen, Susan O’Brien… in Current Hematologic Malignancy Reports (2011)

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    Article

    Survival Advantage in CLL with Frontline FCR Therapy

    Susan O’Brien in Current Hematologic Malignancy Reports (2011)

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    Article

    Burkitt Lymphoma and Atypical Burkitt or Burkitt-like Lymphoma: Should These be Treated as Different Diseases?

    Burkitt lymphoma (BL) is a mature B-cell non-Hodgkin lymphoma with an aggressive clinical course. Since the advent of short, intensive, multiagent chemoimmunotherapy regimens, it has carried a favorable progno...

    Deborah A. Thomas, Susan O’Brien, Stefan Faderl… in Current Hematologic Malignancy Reports (2011)

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    Article

    Novel therapies for relapsed acute lymphoblastic leukemia

    The outcome of salvage therapy for relapsed acute lymphoblastic leukemia (ALL) remains poor. Salvage therapy mimics regimens with activity in newly diagnosed ALL. Novel strategies under investigation as monoth...

    Amber Fullmer, Susan O’Brien, Hagop Kantarjian… in Current Hematologic Malignancy Reports (2009)