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  1. Article

    Open Access

    Whole genome linkage disequilibrium maps in cattle

    Bovine whole genome linkage disequilibrium maps were constructed for eight breeds of cattle. These data provide fundamental information concerning bovine genome organization which will allow the design of stud...

    Stephanie D McKay, Robert D Schnabel, Brenda M Murdoch in BMC Genetics (2007)

  2. Article

    Open Access

    An assessment of population structure in eight breeds of cattle using a whole genome SNP panel

    Analyses of population structure and breed diversity have provided insight into the origin and evolution of cattle. Previously, these studies have used a low density of microsatellite markers, however, with th...

    Stephanie D McKay, Robert D Schnabel, Brenda M Murdoch in BMC Genetics (2008)

  3. Article

    Open Access

    High density linkage disequilibrium maps of chromosome 14 in Holstein and Angus cattle

    Linkage disequilibrium (LD) maps can provide a wealth of information on specific marker-phenotype relationships, especially in areas of the genome where positional candidate genes with similar functions are lo...

    Elisa Marques, Robert D Schnabel, Paul Stothard, Davood Kolbehdari in BMC Genetics (2008)

  4. Article

    Open Access

    A 2cM genome-wide scan of European Holstein cattle affected by classical BSE

    Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. Polymorphisms that alter the prion p...

    Brenda M Murdoch, Michael L Clawson, William W Laegreid, Paul Stothard in BMC Genetics (2010)

  5. Article

    Open Access

    Genome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle

    Linkage disequilibrium (LD) between genes at linked or independent loci can occur at gametic and zygotic levels known asgametic LD and zygotic LD, respectively. Gametic LD is well known for its roles in fine-s...

    Qi Jiang, Zhiquan Wang, Stephen S Moore, Rong-Cai Yang in BMC Genetics (2012)

  6. Article

    Open Access

    Evidence for positive selection of taurine genes within a QTL region on chromosome X associated with testicular size in Australian Brahman cattle

    Previous genome-wide association studies have identified significant regions of the X chromosome associated with reproductive traits in two Bos indicus-influenced breeds: Brahman cattle and Tropical Composites. T...

    Russell E Lyons, Nguyen To Loan, Leanne Dierens, Marina R S Fortes in BMC Genetics (2014)

  7. Article

    Open Access

    Genome-wide association for milk production and female fertility traits in Canadian dairy Holstein cattle

    Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genom...

    Shadi Nayeri, Mehdi Sargolzaei, Mohammed K. Abo-Ismail, Natalie May in BMC Genetics (2016)