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  1. Article

    Open Access

    Human canonical CD157/Bst1 is an alternatively spliced isoform masking a previously unidentified primate-specific exon included in a novel transcript

    CD157/Bst1 is a dual-function receptor and β-NAD+-metabolizing ectoenzyme of the ADP-ribosyl cyclase family. Expressed in human peripheral blood neutrophils and monocytes, CD157 interacts with extracellular matri...

    Enza Ferrero, Nicola Lo Buono, Simona Morone, Rossella Parrotta… in Scientific Reports (2017)

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  2. Article

    Open Access

    In vitro dexamethasone treatment does not induce alternative ATM transcripts in cells from Ataxia–Telangiectasia patients

    Short term treatment with low doses of glucocorticoid analogues has been shown to ameliorate neurological symptoms in Ataxia–Telangiectasia (A–T), a rare autosomal recessive multisystem disease that mainly aff...

    Elisa Pozzi, Elisa Giorgio, Cecilia Mancini, Nicola Lo Buono… in Scientific Reports (2020)

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  3. Article

    Open Access

    CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1

    CD157/BST-1 (a member of the ADP-ribosyl cyclase family) is expressed at variable levels in 97% of patients with acute myeloid leukemia (AML), and is currently under investigation as a target for antibody-base...

    Yuliya Yakymiv, Stefania Augeri, Cristiano Bracci, Sara Marchisio… in Scientific Reports (2021)

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