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  1. Article

    Open Access

    IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection

    Initial events after exposure determine HIV-1 disease progression, underscoring a critical need to understand host mechanisms that interfere with initial viral replication. Although associated with chronic HIV...

    Stanley Adoro, Juan R. Cubillos-Ruiz, ** Chen, Maud Deruaz… in Nature Communications (2015)

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    Article

    XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

    This study finds that triple-negative breast cancers (TNBC) show an increased basal level of endoplasmic reticulum stress and activation of the XBP1 branch of the unfolded protein response; furthermore, XBP1 p...

    ** Chen, Dimitrios Iliopoulos, Qing Zhang, Qianzi Tang, Matthew B. Greenblatt… in Nature (2014)