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  1. Article

    Open Access

    Distinct activation mechanisms regulate subtype selectivity of Cannabinoid receptors

    Design of cannabinergic subtype selective ligands is challenging because of high sequence and structural similarities of cannabinoid receptors (CB1 and CB2). We hypothesize that the subtype selectivity of designe...

    Soumajit Dutta, Diwakar Shukla in Communications Biology (2023)

  2. Article

    Open Access

    Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants

    Vaccine hesitancy and emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) esca** vaccine-induced immune responses highlight the urgency for new COVID-19 thera...

    Lianghui Zhang, Soumajit Dutta, Shiqin **ong, Matthew Chan in Nature Chemical Biology (2022)

  3. Article

    Open Access

    Degradation of complex arabinoxylans by human colonic Bacteroidetes

    Some Bacteroidetes and other human colonic bacteria can degrade arabinoxylans, common polysaccharides found in dietary fiber. Previous work has identified gene clusters (polysaccharide-utilization loci, PULs) ...

    Gabriel V. Pereira, Ahmed M. Abdel-Hamid, Soumajit Dutta in Nature Communications (2021)

  4. Article

    Open Access

    Crystallization of gas-selective nanoporous graphene by competitive etching and growth: a modeling study

    A robust synthesis methodology for crystallizing nanoporous single-layer graphene hosting a high density of size-selective nanopores is urgently needed to realize the true potential of two-dimensional membrane...

    Soumajit Dutta, Mohammad Tohidi Vahdat, Mojtaba Rezaei in Scientific Reports (2019)