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Article
Open AccessDistinct activation mechanisms regulate subtype selectivity of Cannabinoid receptors
Design of cannabinergic subtype selective ligands is challenging because of high sequence and structural similarities of cannabinoid receptors (CB1 and CB2). We hypothesize that the subtype selectivity of designe...
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Article
Open AccessEngineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants
Vaccine hesitancy and emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) esca** vaccine-induced immune responses highlight the urgency for new COVID-19 thera...
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Open AccessDegradation of complex arabinoxylans by human colonic Bacteroidetes
Some Bacteroidetes and other human colonic bacteria can degrade arabinoxylans, common polysaccharides found in dietary fiber. Previous work has identified gene clusters (polysaccharide-utilization loci, PULs) ...
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Article
Open AccessCrystallization of gas-selective nanoporous graphene by competitive etching and growth: a modeling study
A robust synthesis methodology for crystallizing nanoporous single-layer graphene hosting a high density of size-selective nanopores is urgently needed to realize the true potential of two-dimensional membrane...