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    Article

    The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

    Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation and phenotype in which no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (sensors for double-stra...

    Koichi Tabeta, Kasper Hoebe, Edith M Janssen, **n Du, Philippe Georgel… in Nature Immunology (2006)

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    Article

    CD14 is required for MyD88-independent LPS signaling

    The recessive mutation 'Heedless' (hdl) was detected in third-generation N-ethyl-N-nitrosourea–mutated mice that showed defective responses to microbial inducers. Macrophages from Heedless homozygotes signaled by...

    Zhengfan Jiang, Philippe Georgel, **n Du, Louis Shamel… in Nature Immunology (2005)