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  1. Article

    Open Access

    Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

    Actin filament associated protein 1 antisense RNA 1 (named AFAP1-AS1) is a long non-coding RNA and overexpressed in many cancers. This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer...

    Yu Zhong, Liting Yang, Fang **ong, Yi He… in Signal Transduction and Targeted Therapy (2021)

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  2. Article

    Open Access

    Elevated expression of mcl-1 inhibits apoptosis and predicts poor prognosis in patients with surgically resected non-small cell lung cancer

    Mcl-1, an anti-apoptotic member of bcl-2 family, together with cleaved poly (ADC-ribose) polymerase (c-PARP) can serve as a marker of cell apoptosis. Previously we reported that treatment of Mnk inhibitor CGP5...

    Qiuyuan Wen, Yuting Zhan, Hongmei Zheng, Hong**g Zang, Jiadi Luo… in Diagnostic Pathology (2019)

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  3. Article

    Open Access

    A case of eosinophilic granulomatosis with polyangiitis complicated with a similar condition to IgG4 related lung disease

    Atypical manifestations, such as elevated serum immunoglobulin-G4 (IgG4) and extra-pulmonary IgG4 positive plasmacyte infiltration, have been described in patients with eosinophilic granulomatosis with polyang...

    Li Zhou, Fen Cao, Songqing Fan, ** Chen, Shuizi Ding… in BMC Pulmonary Medicine (2019)

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  4. No Access

    Article

    The role of microRNAs in resistance to targeted treatments of non-small cell lung cancer

    Non-small cell lung cancer (NSCLC), accounting for the most of lung cancers, is usually diagnosed in advanced stage. Targeted treatments boost advanced NSCLC patients with certain mutations, but early drug res...

    Hong**g Zang, Weiyuan Wang, Songqing Fan in Cancer Chemotherapy and Pharmacology (2017)

  5. No Access

    Article

    Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomas

    Malignant astrocytomas are able to invade neighboring and distant areas of the normal brain. Signaling pathway alterations play important role in the development of astrocytomas. Deregulation of eukaryotic tra...

    Weibing Fan, Weiyuan Wang, **nfa Mao, Shuzhou Chu, Juan Feng… in Journal of Neuro-Oncology (2017)

  6. Article

    Open Access

    Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma

    The Cks1 protein is an essential factor in regulating cell cycle by mediating the ubiquitination of CDK inhibitor p27kip1. It has been reported that aberrant expression of Cks1 and p27kip1 proteins was found in v...

    Lina Xu, Songqing Fan, ** Zhao, Peng Zhou, Shuzhou Chu, Jiadi Luo… in Diagnostic Pathology (2017)

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  7. No Access

    Article

    Primary unruptured full term ovarian pregnancy with live female infant: case report

    We present a rare case of primary unruptured full term ovarian pregnancy resulting in the delivery of a live female infant and draw attention to the importance of early recognition of primary ovarian pregnancy.

    Jian Huang, **ong **g, Songqing Fan, Zhu Fufan… in Archives of Gynecology and Obstetrics (2011)

  8. No Access

    Article

    Analysis of gene expression identifies candidate molecular markers in nasopharyngeal carcinoma using microdissection and cDNA microarray

    Microarray analysis was used to bring a comprehensive insight into underlying molecular mechanisms and obtain a whole assessment of aberrant gene expression in nasopharyngeal carcinoma (NPC).

    Zhaoyang Zeng, Yanhong Zhou, Wei **ong… in Journal of Cancer Research and Clinical On… (2007)