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  1. Article

    Open Access

    Detection and identification of enterohemorrhagic Escherichia coli O157:H7 and Vibrio cholerae O139 using oligonucleotide microarray

    The rapid and accurate detection and identification of the new subtype of the pathogens is crucial for diagnosis, treatment and control of the contagious disease outbreak. Here, in this study, an approach to d...

    Da-Zhi **, **ao-**g Xu, Su-Hong Chen, Si-Yuan Wen in Infectious Agents and Cancer (2007)

  2. No Access

    Article

    Prokaryotic expression and potential application of the truncated PCV-2 capsid protein

    Three pairs of specific primers were designed to amplify the F2-1, F2-2 and XF2-2 truncated sequences of ORF2 which encodes the capsid protein of porcine circovirus type 2 (PCV-2). The F2-1 sequence had most o...

    Zhong-zi Lou, Zhi-yong Li, Gang Wang, Jian-qiang Li, in Virologica Sinica (2010)

  3. No Access

    Article

    Similar neutralizing activity in the HIV-1 infected long term non-progressors(LTNPs) and typical progressors(TPs)

    Neutralizing antibodies are considered to be an important protective parameter used in HIV-1 vaccine evaluation. However, the exact role that neutralizing antibodies plays in controlling the disease progressio...

    Zheng Wang, Tian-yi Li, **g-yun Li, Li-li Chen, Yong-jian Liu in Virologica Sinica (2012)

  4. No Access

    Article

    CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway

    In this work, we studied the effects of CUB and Sushi multiple domains 1 gene (CSMD1) expression in A375 melanoma cells in vivo and in vitro. CSDM1 expression decreased proliferation and migration, and increas...

    Ming-Rui Tang, Yu-**n Wang, Shu Guo, Si-Yuan Han, Di Wang in Apoptosis (2012)

  5. Article

    Open Access

    FHL1C induces apoptosis in notch1-dependent T-ALL cells through an interaction with RBP-J

    Aberrantly activated Notch signaling has been found in more than 50% of patients with T-cell acute lymphoblastic leukemia (T-ALL). Current strategies that employ γ-secretase inhibitors (GSIs) to target Notch a...

    Wei Fu, Kai Wang, Jun-Long Zhao, Heng-Chao Yu, San-Zhong Li, Yan Lin in BMC Cancer (2014)

  6. Article

    Open Access

    The effects of psychological interventions on depression and anxiety among Chinese adults with cancer: a meta-analysis of randomized controlled studies

    Our previous studies found the high prevalence of depression and anxiety among Chinese cancer patients, and many empirical studies have been conducted to evaluate the effects of psychological interventions on ...

    Yi-Long Yang, Guo-Yuan Sui, Guang-Cong Liu, De-Sheng Huang, Si-Meng Wang in BMC Cancer (2014)

  7. Article

    Open Access

    Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma

    Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is the third leading cause of cancer-related death in human. Alcohol is a known risk factor for HCC. However it is still unclear wh...

    Fei Wang, **-Lian Yang, Ke-ke Yu, Mei Xu, You-zhi Xu, Li Chen in Molecular Cancer (2015)

  8. No Access

    Article

    17β-Estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13

    In our previous study, 17β-estradiol was proved to protect rat annulus fibrosus cells against apoptosis induced by interleukin-1β (IL-1β). However, whether 17β-estradiol has protective effect on rat nucleus pu...

    Si-Dong Yang, Da-Long Yang, Ya-Peng Sun, Bao-Lin Wang, Lei Ma, Shi-Qing Feng in Apoptosis (2015)

  9. No Access

    Article

    Identification of a novel strain of influenza A (H9N2) virus in chicken

    Ning Wang, Zheng Ruan, Yun Wan, Bo Wang, Si-Hua Zhang, **ng-Yi Ge in Virologica Sinica (2015)

  10. Article

    Open Access

    Subdivision of M category for nasopharyngeal carcinoma with synchronous metastasis: time to expand the M categorization system

    The current metastatic category (M) of nasopharyngeal carcinoma (NPC) is a “catch-all” classification, covering a heterogeneous group of tumors ranging from potentially curable to incurable. The aim of this st...

    Lu-Jun Shen, Si-Yang Wang, Guo-Feng **e, Qi Zeng, Chen Chen in Chinese Journal of Cancer (2015)

  11. Article

    Open Access

    Prognostic role of the ABO blood types in Chinese patients with curatively resected non-small cell lung cancer: a retrospective analysis of 1601 cases at a single cancer center

    A positive association between the ABO blood types and survival has been suggested in several malignancies. The aim of this study was to assess the role of the ABO blood types in predicting the prognosis of Ch...

    Ning Li, Miao Xu, Chao-Feng Li, Wei Ou, Bao-**ao Wang in Chinese Journal of Cancer (2015)

  12. Article

    Open Access

    RETRACTED ARTICLE: MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45α

    MicroRNAs (miR, miRNAs) play pivotal roles in numerous physiological and pathophysiological contexts. We investigated whether miR-362-5p act as an oncogene in chronic myeloid leukaemia (CML) and aimed to under...

    Peng Yang, Fang Ni, Rui-qing Deng, Guo Qiang, Hua Zhao, Ming-zhen Yang in Molecular Cancer (2015)

  13. Article

    Open Access

    Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21

    Epidermal growth factor receptor (EGFR) mutations, including a known exon 19 deletion (19 del) and exon 21 L858R point mutation (L858R mutation), are strong predictors of the response to EGFR tyrosine kinase inhi...

    Jiang-Yong Yu, Si-Fan Yu, Shu-Hang Wang, Hua Bai, Jun Zhao in Chinese Journal of Cancer (2016)

  14. Article

    Open Access

    Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma

    Forkhead Box P3 (Foxp3) is a regulatory T cells marker, and its expression correlates with prognosis in a number of malignancies. The aim of this study is to determine the relationship of Foxp3 expression with...

    **g-**g Song, Si-Jia Zhao, Juan Fang, Da Ma, **ang-Qi Liu, **ao-Bing Chen in BMC Cancer (2016)

  15. Article

    Open Access

    Identification of endonuclease domain-containing 1 as a novel tumor suppressor in prostate cancer

    Endonuclease domain containing 1 (ENDOD1) is implicated in tumorigenesis and aggressiveness of multiple tumors. In this study, we aimed to investigate the role of ENDOD1 in prostate cancer (PCa).

    Jianguang Qiu, Shubin Peng, Jie Si-Tu, Cheng Hu, Wentao Huang, Yunhua Mao in BMC Cancer (2017)

  16. Article

    Open Access

    Erratum to: Identification of endonuclease domain-containing 1 as a novel tumor suppressor in prostate cancer

    Jianguang Qiu, Shubin Peng, Jie Si-Tu, Cheng Hu, Wentao Huang, Yunhua Mao in BMC Cancer (2017)

  17. Article

    Open Access

    Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein–Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma

    According to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system, over 50% of patients with nasopharyngeal carcinoma (NPC) have N1 disease at initial diagnosis. However, patients wi...

    Ji-** Yao, Guan-Qun Zhou, Ya-Qin Wang, Si-Yang Wang in Chinese Journal of Cancer (2017)

  18. Article

    Open Access

    The detrimental effects of radiotherapy interruption on local control after concurrent chemoradiotherapy for advanced T-stage nasopharyngeal carcinoma: an observational, prospective analysis

    Previous studies have reported radiotherapy interruption (RTI) is associated with poor local control in two-dimensional radiotherapy (2DRT) era. However, it remains unclear whether RTI still affects local cont...

    Ji-** Yao, Ya-Nan **, Si-Yang Wang, Fan Zhang, Guan-Qun Zhou in BMC Cancer (2018)

  19. Article

    Open Access

    miR-4317 suppresses non-small cell lung cancer (NSCLC) by targeting fibroblast growth factor 9 (FGF9) and cyclin D2 (CCND2)

    Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. MicroRNAs (miRNAs) have been indicated as crucial actors in cancer biology. Accumulating evidence suggests that miRNAs can be used as d...

    ** He, Si-yuan Chen, Zhao Yang, Jie Zhang in Journal of Experimental & Clinical Cancer … (2018)

  20. No Access

    Article

    Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer’s disease

    The study is aimed to assess whether the addition of contourlet-based hippocampal magnetic resonance imaging (MRI) texture features to multivariant models improves the classification of Alzheimer’s disease (AD...

    Ni Gao, Li-**n Tao, Jian Huang, Feng Zhang, **a Li in Metabolic Brain Disease (2018)

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