131 Result(s)
within
Biochemistry, general
Neurosciences
Si**g Pan
Article
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Article
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis
Sepsis-associated encephalopathy (SAE) develops in 30–70% of hospitalized patients with sepsis. In intensive care units (ICUs), propofol is often administered to ensure an appropriate level of sedation in mech...
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Article
A working memory model based on recurrent neural networks using reinforcement learning
Numerous electrophysiological experiments have reported that the prefrontal cortex (PFC) is involved in the process of working memory. PFC neurons continue firing to maintain stimulus information in the delay ...
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Article
Open AccessTemporal-spatial deciphering mental subtraction in the human brain
Mental subtraction, involving numerical processing and operation, requires a complex interplay among several brain regions. Diverse studies have utilized scalp electroencephalograph, electrocorticogram, or fun...
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Article
Machine to brain: facial expression recognition using brain machine generative adversarial networks
The human brain can effectively perform Facial Expression Recognition (FER) with a few samples by utilizing its cognitive ability. However, unlike the human brain, even the well-trained deep neural network is ...
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Article
Short-length SSVEP data extension by a novel generative adversarial networks based framework
Steady-state visual evoked potentials (SSVEPs) based brain–computer interface (BCI) has received considerable attention due to its high information transfer rate (ITR) and available quantity of targets. Howeve...
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The role of extracellular glutamate homeostasis dysregulated by astrocyte in epileptic discharges: a model evidence
Glutamate (Glu) is a predominant excitatory neurotransmitter that acts on glutamate receptors to transfer signals in the central nervous system. Abnormally elevated extracellular glutamate levels is closely re...
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Article
Therapeutic efficacy and pharmacological mechanism of Yindan **nnaotong soft capsule on acute ischemic stroke: a meta-analysis and network pharmacology analysis
Yindan **nnaotong soft capsule (YDXNT), a traditional Chinese medicine preparation, has shown a promising effect in the treatment of acute ischemic stroke (AIS). The goal of this study was to investigate the t...
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The design and implementation of multi-character classification scheme based on EEG signals of visual imagery
In visual-imagery-based brain–computer interface (VI-BCI), there are problems of singleness of imagination task and insufficient description of feature information, which seriously hinder the development and a...
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Article
Open AccessAkt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia
White matter dysplasia (WMD) in preterm infants due to intrauterine inflammation is caused by excessive apoptosis of oligodendrocyte precursor cells (OPCs). In recent years, studies have found that excessive a...
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Article
The decoder design and performance comparative analysis for closed-loop brain–machine interface system
Brain–machine interface (BMI) can convert electroencephalography signals (EEGs) into the control instructions of external devices, and the key of control performance is the accuracy and efficiency of decoder. ...
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Article
Spike-spindle coupling during sleep and its mechanism explanation in childhood focal epilepsy
Childhood focal epilepsy (CFE) is a serious neurological disorder characterized by epileptic seizures arising from a focal or multi-focal zone of the brain in clinics. During non-rapid eye movement (NREM) slee...
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Article
Correction to: Necrostatin-1s Suppresses RIPK1-Driven Necroptosis and Inflammation in Periventricular Leukomalacia Neonatal Mice
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Article
Necrostatin-1s Suppresses RIPK1-driven Necroptosis and Inflammation in Periventricular Leukomalacia Neonatal Mice
Periventricular leukomalacia (PVL), a predominant form of brain injury in preterm survivors, is characterized by hypomyelination and microgliosis and is also the major cause of long-term neurobehavioral abnorm...
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Article
RETRACTED ARTICLE: Edge intelligence-based public health influenza pandemic risk prediction
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Article
Proteomic advance of ischemic stroke: preclinical, clinical, and intervention
Ischemic stroke (IS) is the most common type of stroke and is characterized by high rates of mortality and long-term injury. The prediction and early diagnosis of IS are therefore crucial for optimal clinical ...
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Article
Identification and functional characterization of a novel TRPA1 gene from sea cucumber Apostichopus japonicus and interaction with miR-2013 in response to salt stress
Salinity is important abiotic factor influencing sea cucumber aquaculture. This study aimed to identify and functional study of a novel transient receptor potential cation channel subfamily A member 1 (TRPA1) inv...
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Article
IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts
This study aims to investigate the effect of insulin-like growth factor 1 (IGF-1) combined with osteopontin (OPN) on the protein expression levels and growth of neuronal axons and its possible mechanism. In th...
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Article
Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation
Parkinson disease (PD) is an age-related neurodegenerative disease, which is associated with the loss of dopaminergic neurons (DA neurons) in the substantia nigra pars compacta (SNpc), and neuroinflammation ma...
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Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model
Although the beneficial effects of curcumin, extracted from rhizomes of the ginger family genus Curcuma, on the repair and regeneration of nerves have been evaluated in vitro, there are few studies concerning its...
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Microglial and Neuronal Cell Pyroptosis Induced by Oxygen–Glucose Deprivation/Reoxygenation Aggravates Cell Injury via Activation of the Caspase-1/GSDMD Signaling Pathway
Pyroptosis is a new type of programmed cell death, which induces a strong pro-inflammatory reaction. However, the mechanism of pyroptosis after brain ischemia/reperfusion (I/R) and the interaction between diff...
