Skip to main content

92 Result(s)

within Article Remove this filter Si**g Pan Remove this filter Biochemistry, general Remove this filter Neurology Remove this filter Neurosciences Remove this filter

previous disabled Page of 5
and

  1. No Access

    Article

    Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis

    Sepsis-associated encephalopathy (SAE) develops in 30–70% of hospitalized patients with sepsis. In intensive care units (ICUs), propofol is often administered to ensure an appropriate level of sedation in mech...

    Ye Zhou, Yangliang Yang, Liang Yi, Mengzhi Pan, Weiqing Tang… in Neurochemical Research (2024)

  2. No Access

    Article

    Therapeutic efficacy and pharmacological mechanism of Yindan **nnaotong soft capsule on acute ischemic stroke: a meta-analysis and network pharmacology analysis

    Yindan **nnaotong soft capsule (YDXNT), a traditional Chinese medicine preparation, has shown a promising effect in the treatment of acute ischemic stroke (AIS). The goal of this study was to investigate the t...

    Fangjie Yang, **nmin Li, Junzi Long, Qian Gao, Mengyang Pan… in Metabolic Brain Disease (2024)

  3. Article

    Open Access

    Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia

    White matter dysplasia (WMD) in preterm infants due to intrauterine inflammation is caused by excessive apoptosis of oligodendrocyte precursor cells (OPCs). In recent years, studies have found that excessive a...

    Zhongni Li, Feng Zhang, Li Huang, Jiehong Deng, Yutong Pan… in Neurochemical Research (2024)

    Download PDF (2223 KB) View Article

  4. Article

    Correction to: Necrostatin-1s Suppresses RIPK1-Driven Necroptosis and Inflammation in Periventricular Leukomalacia Neonatal Mice

    **** Sun, Wei Wang, Quanrui Ma, **aoli Pan, Hualiang Zhai… in Neurochemical Research (2024)

    Download PDF (338 KB) View Article

  5. No Access

    Article

    Necrostatin-1s Suppresses RIPK1-driven Necroptosis and Inflammation in Periventricular Leukomalacia Neonatal Mice

    Periventricular leukomalacia (PVL), a predominant form of brain injury in preterm survivors, is characterized by hypomyelination and microgliosis and is also the major cause of long-term neurobehavioral abnorm...

    **** Sun, Wei Wang, Quanrui Ma, **aoli Pan, Hualiang Zhai… in Neurochemical Research (2024)

  6. No Access

    Article

    Proteomic advance of ischemic stroke: preclinical, clinical, and intervention

    Ischemic stroke (IS) is the most common type of stroke and is characterized by high rates of mortality and long-term injury. The prediction and early diagnosis of IS are therefore crucial for optimal clinical ...

    Tian Zhao, **g**g Zeng, Ruijie Zhang, Liyuan Pu, Han Wang… in Metabolic Brain Disease (2023)

  7. No Access

    Article

    IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts

    This study aims to investigate the effect of insulin-like growth factor 1 (IGF-1) combined with osteopontin (OPN) on the protein expression levels and growth of neuronal axons and its possible mechanism. In th...

    Qin Zhao, Hong Su, Wei Jiang, Haodong Luo, Lu Pan, Yuan Liu… in Neurochemical Research (2023)

  8. No Access

    Article

    Wuzi Yanzong Pill relieves MPTP-induced motor dysfunction and neuron loss by inhibiting NLRP3 inflammasome-mediated neuroinflammation

    Parkinson disease (PD) is an age-related neurodegenerative disease, which is associated with the loss of dopaminergic neurons (DA neurons) in the substantia nigra pars compacta (SNpc), and neuroinflammation ma...

    Tao Pan, Qi **ao, Hui-Jie Fan, Lei Xu, Shao-Chen Qin… in Metabolic Brain Disease (2023)

  9. No Access

    Article

    Effects of Curcumin on Axon Growth and Myelin Sheath Formation in an In Vitro Model

    Although the beneficial effects of curcumin, extracted from rhizomes of the ginger family genus Curcuma, on the repair and regeneration of nerves have been evaluated in vitro, there are few studies concerning its...

    Luchen Yang, Zhengju Ren, Pan Song, Zhenghuan Liu, Zhufeng Peng… in Neurochemical Research (2023)

  10. No Access

    Article

    Microglial and Neuronal Cell Pyroptosis Induced by Oxygen–Glucose Deprivation/Reoxygenation Aggravates Cell Injury via Activation of the Caspase-1/GSDMD Signaling Pathway

    Pyroptosis is a new type of programmed cell death, which induces a strong pro-inflammatory reaction. However, the mechanism of pyroptosis after brain ischemia/reperfusion (I/R) and the interaction between diff...

    Zhaofei Dong, Qingxia Peng, Kuang Pan, Weijye Lin, Yidong Wang in Neurochemical Research (2023)

  11. No Access

    Article

    CircRNA-104718 promotes glioma malignancy through regulation of miR-218-5p/HMGB1 signalling pathway

    Increasing number of studies have proven that circular RNAs (circRNAs) play a major role in the biological processes of many different cancers, including glioma, especially as competitive molecular sponges of ...

    Yunji Yan, Hongyu Wang, Jianhong Hu, Tianxue Guo, Qiang Dong… in Metabolic Brain Disease (2023)

  12. No Access

    Article

    Neuroprotective effect of hyperoside in MPP+/MPTP -induced dopaminergic neurodegeneration

    Parkinson’s disease (PD) is a neurodegenerative disease characterized by the pathological loss of nigrostriatal dopaminergic neurons, which causes an insufficient release of dopamine (DA) and then induces moto...

    **ng-Jie Xu, Tao Pan, Hui-Jie Fan, Xu Wang, Jie-Zhong Yu… in Metabolic Brain Disease (2023)

  13. Article

    Munc18-1 Contributes to Hippocampal Injury in Septic Rats Through Regulation of Syntanxin1A and Synaptophysin and Glutamate Levels

    Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction closely associated with mortality in the acute phase of sepsis. Abnormal neurotransmitters release, such as glutamate, plays a crucial role...

    Fajuan Tang, Lin Chen, Hu Gao, Yupeng Lei, Linli Pan… in Neurochemical Research (2023)

    Download PDF (5682 KB) View Article

  14. No Access

    Article

    Tetramethylpyrazine protects neural stem cells against sevoflurane-induced toxicity through Akt/GSK-3β pathway

    Sevoflurane, a commonly used anesthetic, has been found to cause neural stem cell (NSC) injury, thereby contributing to neurocognitive impairment following general anesthesia. Tetramethylpyrazine (TMP), one of...

    Yan Feng, Kui Wang, Ning Wang, Pengyu Jia, Lei Zhang… in Metabolic Brain Disease (2022)

  15. Article

    Open Access

    Selenium Alleviates Cerebral Ischemia/Reperfusion Injury by Regulating Oxidative Stress, Mitochondrial Fusion and Ferroptosis

    To clarify the potential role of selenium (Se) on cerebral ischemia/reperfusion (I/R) injury, we utilized mouse middle cerebral artery occlusion (MCAO) followed by reperfusion as an animal model and oxygen–glu...

    Yuanyuan Shi, Lijian Han, **anxian Zhang, Lili **e, **lei Pan… in Neurochemical Research (2022)

    Download PDF (2721 KB) View Article

  16. No Access

    Article

    Circular RNA circ_0021001 regulates miR-148b-3p/GREM1 axis to modulate proliferation and apoptosis of vascular smooth muscle cells

    Intracranial aneurysm (IA) is an abnormal expression in the intracranial arteries, which is related to the growth and apoptosis of vascular smooth muscle cells (VSMCs). Circular RNA (circRNA) circ_0021001 (als...

    Kui Wang, Gaofeng Tan, Renfu Tian, Han Zhou, Chunhui **ang… in Metabolic Brain Disease (2022)

  17. No Access

    Article

    miR-223 Enhances the Neuroprotection of Estradiol Against Oxidative Stress Injury by Inhibiting the FOXO3/TXNIP Axis

    Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder characterized by complex pathogenesis, of which oxidative stress has long been regarded as a major mechanism. Previously, the protective e...

    Qiong Pan, Jiezhi Ma, Ke Guo in Neurochemical Research (2022)

  18. No Access

    Article

    Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis

    Sevoflurane is a common used inhaled anesthetic that was reported to regulate the progression of multiple cancers. Here, we aimed to investigate the function and regulatory mechanism underlying sevoflurane in ...

    Haili Wang, Guofang Cheng, Lili Quan, Haibo Qu, Ailing Yang… in Metabolic Brain Disease (2022)

  19. No Access

    Article

    Circ_0003611 acts as a miR-885-5p sponge to aggravate the amyloid-β-induced neuronal injury in Alzheimer’s disease

    Alzheimer’s disease (AD) is a chronic degenerative disease in the central nervous system and circular RNAs (circRNAs) are identified as essential regulators in AD. The current research was designed for explora...

    Weihua Pan, Yirui Hu, Lihong Wang, **g Li in Metabolic Brain Disease (2022)

  20. No Access

    Article

    The Effect of α7nAChR Signaling on T Cells and Macrophages and Their Clinical Implication in the Treatment of Rheumatic Diseases

    Rheumatoid arthritis (RA) is one of the most common autoimmune disease and until now, the etiology and pathogenesis of RA is not fully understood, although dysregulation of immune cells is one of the leading c...

    Shu Pan, Yi-** Wu, Sa-Sa Zhang, **u-** Cheng… in Neurochemical Research (2022)

previous disabled Page of 5