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  1. Article

    Open Access

    Structure and evolution of double minutes in diagnosis and relapse brain tumors

    Double minute chromosomes are extrachromosomal circular DNA fragments frequently found in brain tumors. To understand their evolution, we characterized the double minutes in paired diagnosis and relapse tumors...

    Ke Xu, Liang Ding, Ti-Cheng Chang, Ying Shao, Jason Chiang… in Acta Neuropathologica (2019)

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    Article

    Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

    Low-grade neuroepithelial tumors (LGNTs) are diverse CNS tumors presenting in children and young adults, often with a history of epilepsy. While the genetic profiles of common LGNTs, such as the pilocytic astr...

    Ibrahim Qaddoumi, Wilda Orisme, Ji Wen, Teresa Santiago… in Acta Neuropathologica (2016)