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  1. Article

    Open Access

    Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression

    Programmed death-ligand 1 (PD-L1) ensures that tumor cells escape T-cell-mediated tumor immune surveillance. However, gliomas are characteristic of the low immune response and high-resistance therapy, it is ne...

    Shengwen Long, Guixiang Huang, Mi Ouyang, Kai **ao, Hao Zhou… in Cell Death & Disease (2023)

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    Article

    TNFAIP1 Is Upregulated in APP/PS1 Mice and Promotes Apoptosis in SH-SY5Y Cells by Binding to RhoB

    Alzheimer’s disease (AD) poses a significant threat to human life and health. The intraneuronal accumulation of β-amyloid (Aβ) plaques in the brains of AD patients results in neuronal cell death, which is a ke...

    Ye **ao, Yadan Li, Huihui Zhang, Li** Yang… in Journal of Molecular Neuroscience (2021)

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    Article

    TNFAIP1 Mediates Formaldehyde-Induced Neurotoxicity by Inhibiting the Akt/CREB Pathway in N2a Cells

    Formaldehyde (FA) is a common air pollutant. Exposure to exogenous FA can cause damage to the nervous system, such as learning and memory impairment, balance dysfunction, and sleep disorders. Excessive product...

    Junzhi Yi, Min Zhu, Feng Qiu, Yubo Zhou, Pan Shu, Ning Liu… in Neurotoxicity Research (2020)