1,198 Result(s)
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Sen-**g Chen
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Development and validation the Problematic ChatGPT Use Scale: a preliminary report
The ChatGPT (Chat Generative Pre-Trained Transformer) has been rapidly develo** with a growing number of users. The potential for problematic use/dependence caused by the use of ChatGPT urgently needs to be ...
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Open AccessZero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering
Mutations in amino acid sequences can provoke changes in protein function. Accurate and unsupervised prediction of mutation effects is critical in biotechnology and biomedicine, but remains a fundamental chall...
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Different effects of Al on the decomposition of HATO under non-isothermal and adiabatic conditions
Explosives containing Al powder have higher detonation energy and heat. However, while pursuing detonation performances, the thermal safety of explosives with Al is equally important. To research the effect of...
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A Novel Method to Enhance the Content and size of Y-211 Particles in YBCO bulk Superconductors Grown by RE+011 TSIG Process
In this research, a novel method to improve the particle size and content of Y2BaCuO5 (Y-211) in YBa2Cu3O7 − x (YBCO) bulks was demonstrated. The single-domain YBCO bulks (20 mm in diameter) have been fabricated ...
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Open AccessSearch for central exclusive production of top quark pairs in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with tagged protons
A search for the central exclusive production of top quark-antiquark pairs ( t t ...
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Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
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Open AccessObservation of heat pum** effect by radiative shuttling
Heat shuttling phenomenon is characterized by the presence of a non-zero heat flow between two bodies without net thermal bias on average. It was initially predicted in the context of nonlinear heat conduction...
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Open AccessComparative optimization of polysaccharide-based nanoformulations for cardiac RNAi therapy
Ionotropic gelation is widely used to fabricate targeting nanoparticles (NPs) with polysaccharides, leveraging their recognition by specific lectins. Despite the fabrication scheme simply involves self-assembl...
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Open AccessQuantitative assessment of the associations between DNA repair gene XRCC3 Thr241Met polymorphism and pancreatic cancer
Prior research exploring the correlation between the XRCC3 Thr241Met polymorphism and the susceptibility to pancreatic cancer has yielded conflicting outcomes. To date, there has been a notable absence of stud...
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Open AccessA complete reference genome of broomcorn millet
Broomcorn millet (Panicum miliaceum L.), known for its traits of drought resistance, adaptability to poor soil, short growth period, and high photosynthetic efficiency as a C4 plant, represents one of the earlies...
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Open AccessCommon dietary emulsifiers promote metabolic disorders and intestinal microbiota dysbiosis in mice
Dietary emulsifiers are linked to various diseases. The recent discovery of the role of gut microbiota–host interactions on health and disease warrants the safety reassessment of dietary emulsifiers through th...
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Open AccessSearch for heavy neutral leptons in final states with electrons, muons, and hadronically decaying tau leptons in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for heavy neutral leptons (HNLs) of Majorana or Dirac type using proton-proton collision data at ...
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Open AccessSearch for the decay of the Higgs boson to a pair of light pseudoscalar bosons in the final state with four bottom quarks in proton-proton collisions at \( \sqrt{\textrm{s}} \) = 13 TeV
A search is presented for the decay of the 125 GeV Higgs boson (H) to a pair of new light pseudoscalar bosons (a), followed by the prompt decay of each a boson to a bottom quark-antiquark pair,
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Open AccessAn improved genome assembly of Chrysanthemum nankingense reveals expansion and functional diversification of terpene synthase gene family
Terpenes are important components of plant aromas, and terpene synthases (TPSs) are the key enzymes driving terpene diversification. In this study, we characterized the volatile terpenes in five different Chrysan...
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Open AccessSphingosine d18:1 promotes nonalcoholic steatohepatitis by inhibiting macrophage HIF-2α
Non-alcoholic steatohepatitis (NASH) is a severe type of the non-alcoholic fatty liver disease (NAFLD). NASH is a growing global health concern due to its increasing morbidity, lack of well-defined biomarkers ...
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Patient-Reported Reasons for Sending Portal Messages: A Survey of Use in a Family Medicine Department
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Preparation of yttrium oxide coating with enhanced thermal shock resistance on refractories used for titanium alloy melting and casting
In order to enhance the service life of refractories for melting and casting of titanium alloy, preparation of yttrium oxide coatings on the refractories surface is an effective solution. The improvement of th...
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Mechanism Exploration of Euphorbia fischeriana Steud. for Liver Cancer Based on Aspartic Acid Identification in Metabolomics
To investigate the anti-liver cancer effects and aspartic acid (Asp)-related action mechanism of Euphorbia fischeriana Steud. (Lang Du, LD).
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Universal and efficient hybrid modeling and direct slicing method for additive manufacturing processes
Model design and slicing contour generation in additive manufacturing (AM) data processing face challenges in terms of efficiency and scalability when stereolithography files generated by complex functionally ...
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The aged tumor microenvironment limits T cell control of cancer
The etiology and effect of age-related immune dysfunction in cancer is not completely understood. Here we show that limited priming of CD8+ T cells in the aged tumor microenvironment (TME) outweighs cell-intrinsi...
