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Article
Preference for anti-phospholipase A2 receptor antibody assay in patients with suspected membranous nephropathy: a survey study on medical practice after publication of Japanese Guidelines for Nephrotic Syndrome 2020
International practice guidelines advocate for the use of anti-phospholipase A2 receptor (PLA2R) antibody testing to diagnose primary membranous nephropathy (pMN). This study aimed to clarify the current statu...
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Article
Perspectives on the optimal timing of advance care planning among Japanese patients undergoing dialysis and clinicians: a cross-sectional study
The majority of dialysis patients and clinicians favor early advance care planning in our sample. Yet, there is a disconnect: only 11% of patients discussed future care with their clinicians. Our findings indi...
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Article
Practice patterns of rituximab for primary membranous nephropathy 2021 in Japan: a web-based survey of board-certified nephrologists
Although rituximab (RTX) is recommended by kidney disease improving global outcomes as one of the standard therapies for primary membranous nephropathy (pMN), given the constraint of insurance coverage, it is ...
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Article
Association between inpatient education program for patients with pre-dialysis chronic kidney disease and new-onset cardiovascular disease after initiating dialysis
The association between inpatient education programs (IEPs) for patients with pre-dialysis chronic kidney disease (CKD) and new-onset cardiovascular disease (CVD) after initiating dialysis is unclear.
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Article
Marked hyperkalemia due to inappropriate blood sample storage in two suspected cases of familial pseudohyperkalemia
We herein report two suspected cases of pseudohyperkalemia who presented with severe hyperkalemia examined at small primary care clinics; however, re-exams at a tertiary care hospital showed normal potassium l...
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Article
Japanese clinical practice patterns of primary nephrotic syndrome 2021: a web-based questionnaire survey of certified nephrologists
With the publication of the “Evidence-Based Clinical Practice Guideline for Nephrotic Syndrome 2020,” we examined nephrologists’ adherence to the recommendations of four of its clinical questions (CQs).
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Article
Initiation of renin–angiotensin system inhibitors and first complete remission in patients with primary nephrotic syndrome: a nationwide cohort study
Evidence on renin–angiotensin system inhibitors (RASis) effect in reducing urinary protein levels in patients with nephrotic syndrome is insufficient. We determined whether RASis can induce complete remission ...
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Article
Impact of inpatient educational programs on mortality after the start of dialysis therapy
Although inpatient educational programs (IEPs) for non-dialysis-dependent chronic kidney disease (CKD) have been reported to slow disease progression, their legacy effect on prognosis after the start of dialys...
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Article
Resting respiration rate predicts all-cause mortality in older outpatients
Although respiratory rate has been a sensitive predictor for prognosis in acute settings, resting respiratory rate (RRR) is undervalued in chronic care. The clinical significance of RRR among older people is n...
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Article
A digest of the Evidence-Based Clinical Practice Guideline for Nephrotic Syndrome 2020
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Article
Open AccessAssociation of glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS): a cross-sectional study
While survival of systemic lupus erythematosus (SLE) patients has improved substantially, problems remain in the management of their emotional health. Medium to high-dose glucocorticoid doses are known to wors...
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Article
A questionnaire on prescription patterns of proton pump inhibitors for hemodialysis patients in Japan
Proton pump inhibitors (PPIs) are widely used in the general population often without an endpoint. The practice of prescribing PPIs in the hemodialysis (HD) population is unknown. Thus, we aimed to identify th...
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Article
Open AccessLength of hospital stay is associated with a decline in activities of daily living in hemodialysis patients: a prospective cohort study
The impact of length of hospital stay on activities of daily living (ADLs) has not specifically been investigated among dialysis patients. Therefore, we attempt to verify the association between the length of ...
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Article
Open AccessPopulation-level associations of achievement of targets for bone-mineral markers with survival in haemodialysis patients with mildly elevated intact-PTH levels: a case-cohort study
Achieving calcium, phosphorus, and intact parathyroid hormone (PTH) targets helps improve dialysis population outcomes. We aimed to assess the population-level associations of achievement of those targets with...
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Article
Open AccessComputed tomography during initial management and mortality among hemodynamically unstable blunt trauma patients: a nationwide retrospective cohort study
Although many hemodynamically unstable trauma patients undergo computed tomography (CT) to identify a source of bleeding, this practice is currently only recommended by a few guidelines. To clarify whether CT ...
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Article
Development of quality indicators for care of chronic kidney disease in the primary care setting using electronic health data: a RAND-modified Delphi method
The prevalence of chronic kidney disease (CKD) has recently increased, and maintaining high quality of CKD care is a major factor in preventing end-stage renal disease. Here, we developed novel quality indicat...
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Article
Open AccessHuman immunodeficiency virus and hepatitis B genotype G/A2 recombinant co-infection: a case study
Hepatitis B virus (HBV) genotypes have distinct geographical distributions and are associated with different clinical courses. HBV genotype G (HBV/G) is extremely rare among Human immunodeficiency virus (HIV) ...
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Article
Open AccessPreferences of young physicians at community hospitals regarding academic research training through graduate school: a cross-sectional research
Desire to attend graduate school for academic research training following the mandatory two-year clinical internship is unknown among young Japanese physicians who work at community hospitals after their inter...
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Article
Intracardiac echocardiography for percutaneous closure of atrial septal defects: initial experiences in Japan
Transcatheter closure of secundum atrial septal defect (ASD) has been widely performed as a less invasive alternative to surgery with zero mortality so far in Japan. In the US and Europe, intracardiac echocard...