31 Result(s)
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Article
S. Baron-Cohen
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Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken words
In 'colored-hearing' synesthesia, individuals report color experiences when they hear spoken words. If the synesthetic color experience resembles that of normal color perception, one would predict activation o...
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Screening Adults for Asperger Syndrome Using the AQ: A Preliminary Study of its Diagnostic Validity in Clinical Practice
The Autism Spectrum Quotient (AQ) has been developed to measure the degree to which an adult with normal intelligence has autistic traits. In this paper it is evaluated for its potential as a screening questio...
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Open AccessA novel functional brain imaging endophenotype of autism: the neural response to facial expression of emotion
Siblings of individuals with autism have over 20 times the population risk of autism. Evidence of comparable, but less marked, cognitive and social communication deficits in siblings suggests a role for these ...
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Sex-specific serum biomarker patterns in adults with Asperger's syndrome
Autism spectrum conditions have been hypothesized to be an exaggeration of normal male low-empathizing and high-systemizing behaviors. We tested this hypothesis at the molecular level by performing comprehensi...
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Identification of a biological signature for schizophrenia in serum
Biomarkers are now used in many areas of medicine but are still lacking for psychiatric conditions such as schizophrenia (SCZ). We have used a multiplex molecular profiling approach to measure serum concentrat...
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Olfactory Detection Thresholds and Adaptation in Adults with Autism Spectrum Condition
Sensory issues have been widely reported in Autism Spectrum Conditions (ASC). Since olfaction is one of the least investigated senses in ASC, the current studies explore olfactory detection thresholds and adap...
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Taste Identification in Adults with Autism Spectrum Conditions
Sensory issues are widely reported in Autism Spectrum Conditions (ASC). Since taste perception is one of the least studied senses in ASC we explored taste identification in adults with ASC (12 males, 11 female...
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Open AccessOxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism
Autism spectrum conditions (autism) affect ~1% of the population and are characterized by deficits in social communication. Oxytocin has been widely reported to affect social-communicative function and its neu...
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Open AccessElevated fetal steroidogenic activity in autism
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish H...
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Open AccessDevelopmental white matter microstructure in autism phenotype and corresponding endophenotype during adolescence
During adolescence, white matter microstructure undergoes an important stage of development. It is hypothesized that the alterations of brain connectivity that have a key role in autism spectrum conditions (AS...
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Open AccessThe psychometric properties of the Quantitative-Checklist for Autism in Toddlers (Q-CHAT) as a measure of autistic traits in a community sample of Singaporean infants and toddlers
There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely t...
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Open AccessBrief Report: The Go/No-Go Task Online: Inhibitory Control Deficits in Autism in a Large Sample
Autism Spectrum Conditions (ASC, also referred to as Autism Spectrum Disorders) entail difficulties with inhibition: inhibiting action, inhibiting one’s own point of view, and inhibiting distractions that may ...
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Open AccessSex differences in frontal lobe connectivity in adults with autism spectrum conditions
Autism spectrum conditions (ASC) are more prevalent in males than females. The biological basis of this difference remains unclear. It has been postulated that one of the primary causes of ASC is a partial dis...
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Open AccessIntranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women
Oxytocin may influence various human behaviors and the connectivity across subcortical and cortical networks. Previous oxytocin studies are male biased and often constrained by task-based inferences. Here, we ...
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‘Emotiplay’: a serious game for learning about emotions in children with autism: results of a cross-cultural evaluation
Children with autism spectrum conditions (ASC) experience difficulties recognizing others’ emotions and mental states. It has been shown that serious games (SG) can produce simplified versions of the socio-emo...
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Child, Maternal and Demographic Factors Influencing Caregiver-Reported Autistic Trait Symptomatology in Toddlers
Current research on children’s autistic traits in the general population relies predominantly on caregiver-report, yet the extent to which individual, caregiver or demographic characteristics are associated wi...
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Open AccessGenome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition
We conducted a genome-wide meta-analysis of cognitive empathy using the ‘Reading the Mind in the Eyes’ Test (Eyes Test) in 88,056 research volunteers of European Ancestry (44,574 females and 43,482 males) from...
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Open AccessA ‘choice’, an ‘addiction’, a way ‘out of the lost’: exploring self-injury in autistic people without intellectual disability
Non-suicidal self-injury (NSSI) describes a phenomenon where individuals inflict deliberate pain and tissue damage to their bodies. Self-injurious behaviour is especially prevalent across the autism spectrum, ...
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Open AccessAutistic traits, resting-state connectivity, and absolute pitch in professional musicians: shared and distinct neural features
Recent studies indicate increased autistic traits in musicians with absolute pitch and a higher proportion of absolute pitch in people with autism. Theoretical accounts connect both of these with shared neural...
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Open AccessA comparative study of autistic and non-autistic women’s experience of motherhood
Autism is a lifelong neurodevelopmental difference and disability, yet there is limited research examining parenting in autistic mothers.
