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Article
Open AccessUrinary phytoestrogen excretion and prostate cancer risk: a nested case–control study in the Multiethnic Cohort
Phytoestrogens are of special interest in prostate cancer research because populations in Asia with a high consumption of phytoestrogens have a lower incidence of the disease than comparable populations in Wes...
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Article
Open AccessProspective study of grapefruit intake and risk of breast cancer in postmenopausal women: the Multiethnic Cohort Study
In vitro and in vivo studies have shown that cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of oestrogens. There is evidence that grapefruit, an inhibitor of CYP3A4, increases plasma oestrogen concent...