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  1. Article

    Open Access

    Age- and sex-specific reference values of biventricular flow components and kinetic energy by 4D flow cardiovascular magnetic resonance in healthy subjects

    Advances in four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) have allowed quantification of left ventricular (LV) and right ventricular (RV) blood flow. We aimed to (1) investigate age and...

    **aodan Zhao, Ru-San Tan, Pankaj Garg in Journal of Cardiovascular Magnetic Resonan… (2023)

  2. Article

    Open Access

    Right ventricular energetic biomarkers from 4D Flow CMR are associated with exertional capacity in pulmonary arterial hypertension

    Cardiovascular magnetic resonance (CMR) offers comprehensive right ventricular (RV) evaluation in pulmonary arterial hypertension (PAH). Emerging four-dimensional (4D) flow CMR allows visualization and quantif...

    **aodan Zhao, Shuang Leng, Ru-San Tan in Journal of Cardiovascular Magnetic Resonan… (2022)

  3. Article

    Open Access

    Ventricular flow analysis and its association with exertional capacity in repaired tetralogy of Fallot: 4D flow cardiovascular magnetic resonance study

    Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) allows quantification of biventricular blood flow by flow components and kinetic energy (KE) analyses. However, it remains unclear whether 4D ...

    **aodan Zhao, Liwei Hu, Shuang Leng in Journal of Cardiovascular Magnetic Resonan… (2022)

  4. Article

    Open Access

    Cardiovascular magnetic resonance‐assessed fast global longitudinal strain parameters add diagnostic and prognostic insights in right ventricular volume and pressure loading disease conditions

    Parameters of myocardial deformation may provide improved insights into right ventricular (RV) dysfunction. We quantified RV longitudinal myocardial function using a fast, semi-automated method and investigate...

    Shuang Leng, Ru-San Tan, Jiajun Guo in Journal of Cardiovascular Magnetic Resonan… (2021)

  5. Article

    Open Access

    Validation of a rapid semi-automated method to assess left atrial longitudinal phasic strains on cine cardiovascular magnetic resonance imaging

    Abnormal left atrial (LA) function is a marker of cardiac dysfunction and adverse cardiovascular outcome, but is difficult to assess, and hence not, routinely quantified. We aimed to determine the feasibility ...

    Shuang Leng, Ru-San Tan, **aodan Zhao in Journal of Cardiovascular Magnetic Resonan… (2018)

  6. Article

    Open Access

    Efficacy and safety of combination therapy with vildagliptin and metformin versus metformin up-titration in Chinese patients with type 2 diabetes mellitus: study design and rationale of the vision study

    Limitations of the currently recommended stepwise treatment pathway for type 2 diabetes mellitus (T2DM), especially the failure of monotherapies to maintain good glycemic control, have prompted use of early, m...

    Li-Nong Ji, Chang-Yu Pan, Ju-Ming Lu, Hong Li, Qiang Li in Cardiovascular Diabetology (2013)