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Effect of glucocorticoids pretreatment on steroidogenic capacity of adrenocortical cells isolated from Meishan piglets

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  1. Article

    Open Access

    NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving

    Under adverse conditions, such as sustained or chronic hyperglycemia or hyperlipidemia, ROS (reactive oxygen species) or/and ER-stress (endoplasmic reticulum stress) will be induced in pancreatic β cells. ROS ...

    Ze-qing Pu, Tian-fu Yu, Dong Liu, Cheng-wen **, Esha Sadiq… in Cell Death Discovery (2021)

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  2. Article

    Open Access

    Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies

    The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important target for vaccine and drug development. However, the rapid emergence of variant strains with mutated S pro...

    Miao-Miao Zhao, Yun Zhu, Li Zhang, Gongxun Zhong, Linhua Tai, Shuo Liu… in Cell Discovery (2022)

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