Skip to main content

4 Result(s)

within English Remove this filter Biomedicine Remove this filter Animal Genetics and Genomics Remove this filter Gene Function Remove this filter Robert L. Wilensky Remove this filter Article Remove this filter

and

  1. No Access

    Article

    Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

    We have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome 10q1. We genotyped 228 microsatellite markers in Icelandic individuals with type 2 diabetes and controls throughout a 10.5-...

    Struan F A Grant, Gudmar Thorleifsson, Inga Reynisdottir… in Nature Genetics (2006)

  2. No Access

    Article

    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

    We recently described an association between risk of type 2diabetes and variants in the transcription factor 7-like 2 gene (TCF7L2; formerly TCF4), with a population attributable risk (PAR) of 17%–28% in three po...

    Agnar Helgason, Snæbjörn Pálsson, Gudmar Thorleifsson, Struan F A Grant… in Nature Genetics (2007)

  3. No Access

    Article

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

    We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases and controls, and we found that a previously described variant in the transcription factor 7-like 2 gene (TCF7L2) gene con...

    Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Inga Reynisdottir… in Nature Genetics (2007)

  4. No Access

    Article

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    We performed a genome-wide association scan to search for sequence variants conferring risk of prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. Follow-up studies involving th...

    Julius Gudmundsson, Patrick Sulem, Valgerdur Steinthorsdottir… in Nature Genetics (2007)