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    Article

    Highly-multiplexed volumetric map** with Raman dye imaging and tissue clearing

    Map** the localization of multiple proteins in their native three-dimensional (3D) context would be useful across many areas of biomedicine, but multiplexed fluorescence imaging has limited intrinsic multipl...

    Lixue Shi, Mian Wei, Yupeng Miao, Naixin Qian, Lingyan Shi in Nature Biotechnology (2022)

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    Evidence that Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species

    Pancreatic islet zinc levels vary widely between species. Very low islet zinc levels in Guinea pigs were thought to be driven by evolution of the INS gene that resulted in the generation of an isoform lacking a h...

    Karin J. Bosma, Kristen E. Syring, James K. Oeser in Journal of Molecular Evolution (2019)