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  1. Article

    Open Access

    Safety and Efficacy of Ribociclib in Combination with Letrozole in Patients with HR+, HER2− Advanced Breast Cancer: Results from the Italian Subpopulation of Phase 3b CompLEEment-1 Study

    Ribociclib plus letrozole demonstrated manageable safety and efficacy profiles in hormone receptor–positive (HR+), human epidermal growth factor receptor-2–negative (HER2−) advanced breast cancer (ABC) in the ...

    Michelino De Laurentiis, Roberta Caputo, Manuelita Mazza in Targeted Oncology (2022)

  2. Article

    Publisher Correction: Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

    Sushree S. Sahoo, Victor B. Pastor, Charnise Goodings, Rebecca K. Voss in Nature Medicine (2021)

  3. No Access

    Article

    Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

    Germline SAMD9 and SAMD9L mutations (SAMD9/9Lmut) predispose to myelodysplastic syndromes (MDS) with propensity for somatic rescue. In this study, we investigated a clinically annotated pediatric MDS cohort (n = ...

    Sushree S. Sahoo, Victor B. Pastor, Charnise Goodings, Rebecca K. Voss in Nature Medicine (2021)

  4. Article

    Open Access

    PONDx: real-life utilization and decision impact of the 21-gene assay on clinical practice in Italy

    Clinicopathological prognostic features have limited value to identify with precision newly diagnosed patients with hormone receptor (HR)-positive, HER2-negative breast cancer (BC), who would benefit from chem...

    Francesco Cognetti, Riccardo Masetti, Alessandra Fabi, Giulia Bianchi in npj Breast Cancer (2021)

  5. Article

    Open Access

    Neoadjuvant PF-05280014 (a potential trastuzumab biosimilar) versus trastuzumab for operable HER2+ breast cancer

    This randomised, double-blind study compared pharmacokinetics, efficacy, safety and immunogenicity of PF-05280014 (potential trastuzumab biosimilar) and trastuzumab reference product (Herceptin) sourced from t...

    Philip E. Lammers, Magdolna Dank, Riccardo Masetti in British Journal of Cancer (2018)