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The relative importance of cyclosporine exposure in heart, kidney or liver transplant recipients on maintenance therapy

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  1. Article

    Open Access

    Are higher antidepressant plasma concentrations associated with fall risk in older antidepressant users?

    To explore the association between antidepressant plasma concentrations and fall risk in older users.

    A. C. Pronk, E. P. van Poelgeest, L. J. Seppala in European Geriatric Medicine (2023)

  2. Article

    Open Access

    In silico evaluation of limited sampling strategies for individualized dosing of extended half-life factor IX concentrates in hemophilia B patients

    Hemophilia B is a bleeding disorder, caused by a factor IX (FIX) deficiency. Recently, FIX concentrates with extended half-life (EHL) have become available. Prophylactic dosing of EHL-FIX concentrates can be o...

    T. Preijers, M. W. F. van Spengler, K. Meijer in European Journal of Clinical Pharmacology (2022)

  3. Article

    Open Access

    Phase I and pharmacokinetic study of the combination of topotecan and ifosfamide administered intravenously every 3 weeks

    To determine the maximum-tolerated dose (MTD), dose-limiting toxicities, and pharmacokinetics of topotecan administered as a 30-min intravenous (i.v.) infusion over 5 days in combination with a 1-h i.v. infusi...

    T Kerbusch, G Groenewegen, R A A Mathôt, V M M Herben in British Journal of Cancer (2004)