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Article
KDR expression is associated with the stage and cigarette smoking of the patients with lung cancer
Kinase insert domain-containing receptor (KDR) is one of the molecular targets used in cancer therapy. We studied the KDR expression characteristics and the relationship with the clinical parameters of the pat...
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Article
Sensitization of SiHa cell to gemcitabine by CD40 activation and its overexpression in cervical carcinoma
CD40, a member of the tumor necrosis factor receptor superfamily, is widely expressed on various cell types. Some studies show that CD40 expression is related to several carcinomas, where its function remains ...
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Article
Posttreatment plasma VEGF levels may be associated with the overall survival of patients with advanced non-small cell lung cancer treated with bevacizumab plus chemotherapy
We sought to find blood-based biomarkers that can be used to predict efficacy in advanced non-small cell lung cancer patients treated with bevacizumab plus chemotherapy. Blood was collected before treatment an...
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Article
Identification of heat shock protein 27 as a radioresistance-related protein in nasopharyngeal carcinoma cells
To identify the proteins involved in radioresistance in nasopharyngeal cancer (NPC) cells.
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Article
Prognostic significance of BRCA1 expression in gastric cancer
The breast and ovarian cancer susceptibility gene 1 (BRCA1) is a well-known tumor suppressor gene implicated in the predisposition of early-onset breast and ovarian cancer. The aim of this study is to identify...
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Article
Tau proteins expressions in advanced breast cancer and its significance in taxane-containing neoadjuvant chemotherapy
Tau is a microtubule-associated protein and expressed in normal breast epithelial cells and breast cancer. Tau expression in breast cancer may be important for chemotherapy optimization. This study is to inves...
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Article
Functional polymorphisms of matrix metalloproteinase-9 and survival in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy
To investigate the prognostic role of major matrix metalloproteinase (MMP) gene polymorphisms in patients with locoregionally advanced nasopharyngeal carcinoma (NPC) treated with chemoradiotherapy. Four hundre...
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Article
Decreased ITIH5 expression is associated with poor prognosis in primary gastric cancer
Inter-α-trypsin inhibitors (ITIs) are a family of serine protease inhibitors that comprise one light chain and a variable set of heavy chains (ITI heavy chains, ITIHs). ITIH5 is a new member of the ITIH family...
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Article
Decreased expression of TRIM3 is associated with poor prognosis in patients with primary hepatocellular carcinoma
Tripartite motif-containing 3 (TRIM3) is a member of the tripartite motif (TRIM) protein family and is reported to be involved in the pathogenesis of various cancers. The role of TRIM3 in hepatocellular carcin...
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Article
SDF-1/CXCR4 promotes F5M2 osteosarcoma cell migration by activating the Wnt/β-catenin signaling pathway
Osteosarcoma (OS), the most common primary malignant bone tumor in children and adolescents, lacks an effective therapy. Stromal cell-derived factor (SDF-1) and its receptor, CXCR4, play multiple roles in migr...
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Article
Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation
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Article
Open AccessDetection of miR-155-5p and imaging lung cancer for early diagnosis: in vitro and in vivo study
Currently, the routine screening program has insufficient capacity for the early diagnosis of lung cancer. Therefore, a type of chitosan-molecular beacon (CS-MB) probe was developed to recognize the miR-155-5p...
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Article
Curcumin combined with arsenic trioxide in the treatment of acute myeloid leukemia: network pharmacology analysis and experimental validation
This study aimed to evaluate the effects of curcumin by co-administration of arsenic trioxide (As2O3) in acute myeloid leukemia (AML) treatment, using network pharmacology and experimental validation.
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Article
Correction to: CXCL6: A potential therapeutic target for inflammation and cancer
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Article
CXCL6: A potential therapeutic target for inflammation and cancer
Chemokines were originally defined as cytokines that affect the movement of immune cells. In recent years, due to the increasing importance of immune cells in the tumor microenvironment (TME), the role of chem...
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Article
Clinical risk factors and prognostic model for patients with bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation
Bronchiolitis obliterans syndrome (BOS) is a common and potentially devastating noninfectious pulmonary complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Currently, predictive ...