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Open AccessThe association between blood lipids and cognitive impairment in type 2 diabetes mellitus
The study was performed to explore the association between blood lipids and cognitive impairment in patients with type 2 diabetes mellitus (T2DM).
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Open AccessCircular RNA circGlis3 protects against islet β-cell dysfunction and apoptosis in obesity
Pancreatic β-cell compensation is a major mechanism in delaying T2DM progression. Here we report the abnormal high expression of circGlis3 in islets of male mice with obesity and serum of people with obesity. ...
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Open AccessPorous microcapsules encapsulating β cells generated by microfluidic electrospray technology for diabetes treatment
Diabetes mellitus is becoming increasingly prevalent worldwide and needs effective clinical treatment methods. β-Cell replacement therapy has become a safe alternative for diabetes treatment in recent years, a...
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Open AccessThe long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
Despite obesity being a predisposing factor for pancreatic β-cell dysfunction and loss, the mechanisms underlying its negative effect on insulin-secreting cells remain poorly understood. In this study, we iden...
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Open AccessActive cell-matrix coupling regulates cellular force landscapes of cohesive epithelial monolayers
Epithelial cells can assemble into cohesive monolayers with rich morphologies on substrates due to competition between elastic, edge, and interfacial effects. Here we present a molecularly based thermodynamic ...
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Article
Open AccessAdiponectin is required for maintaining normal body temperature in a cold environment
Thermogenic impairment promotes obesity and insulin resistance. Adiponectin is an important regulator of energy homeostasis. While many beneficial metabolic effects of adiponectin resemble that of activated th...
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Open AccessEffect of a CGMS and SMBG on Maternal and Neonatal Outcomes in Gestational Diabetes Mellitus: a Randomized Controlled Trial
In this study, we sought to investigate the effects of a continuous glucose monitoring system (CGMS) on maternal and neonatal outcomes. A total of 106 women with gestational diabetes mellitus (GDM) in gestatio...
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Open AccessAnticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways
High levels of thymidine kinase 1 (TK1) and thymidine phosphorylase (TYMP) are key molecular targets by thymidine therapeutics in cancer treatment. The dual roles of TYMP as a tumor growth factor and a key act...
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Open AccessGrowth and Formation Mechanism of Branched Carbon Nanotubes by Pyrolysis of Iron(II) Phthalocyanine
In this letter, a route for synthesizing vertically aligned multi-walled carbon nanotubes (MWCNTs) with branched nanotubes in large area was reported. The branched MWCNTs up to about 30% can be generated by th...
