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Article

Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways

High levels of thymidine kinase 1 (TK1) and thymidine phosphorylase (TYMP) are key molecular targets by thymidine therapeutics in cancer treatment. The dual roles of TYMP as a tumor growth factor and a key act...

Qiong Wei, Haijuan Liu, Honghao Zhou, Dejun Zhang, Zhiwei Zhang, Qibing Zhou in BMC Cancer (2015)