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Article
RBM15 Knockdown Impairs the Malignancy of Cervical Cancer by Mediating m6A Modification of Decorin
Cervical cancer (CC) is considered to be the most prevalent female malignancies across the globe and a prime cause of mortality among women. RNA-binding motif protein 15 (RBM15) has been elucidated to particip...
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Article
Open AccessThe association between blood lipids and cognitive impairment in type 2 diabetes mellitus
The study was performed to explore the association between blood lipids and cognitive impairment in patients with type 2 diabetes mellitus (T2DM).
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Article
Open AccessCircular RNA circGlis3 protects against islet β-cell dysfunction and apoptosis in obesity
Pancreatic β-cell compensation is a major mechanism in delaying T2DM progression. Here we report the abnormal high expression of circGlis3 in islets of male mice with obesity and serum of people with obesity. ...
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Article
LSTM-TCN: dissolved oxygen prediction in aquaculture, based on combined model of long short-term memory network and temporal convolutional network
Dissolved oxygen (DO) is an important water quality monitoring parameter of great significance in aquaculture. Accurate prediction of dissolved oxygen can help farmers to take necessary measures in advance to ...
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Article
Open AccessPorous microcapsules encapsulating β cells generated by microfluidic electrospray technology for diabetes treatment
Diabetes mellitus is becoming increasingly prevalent worldwide and needs effective clinical treatment methods. β-Cell replacement therapy has become a safe alternative for diabetes treatment in recent years, a...
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Article
Open AccessThe long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice
Despite obesity being a predisposing factor for pancreatic β-cell dysfunction and loss, the mechanisms underlying its negative effect on insulin-secreting cells remain poorly understood. In this study, we iden...
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Article
An eight-lncRNA signature predicts survival of breast cancer patients: a comprehensive study based on weighted gene co-expression network analysis and competing endogenous RNA network
To identify a lncRNA signature to predict survival of breast cancer (BRCA) patients.
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Article
Open AccessActive cell-matrix coupling regulates cellular force landscapes of cohesive epithelial monolayers
Epithelial cells can assemble into cohesive monolayers with rich morphologies on substrates due to competition between elastic, edge, and interfacial effects. Here we present a molecularly based thermodynamic ...
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Article
Open AccessAdiponectin is required for maintaining normal body temperature in a cold environment
Thermogenic impairment promotes obesity and insulin resistance. Adiponectin is an important regulator of energy homeostasis. While many beneficial metabolic effects of adiponectin resemble that of activated th...
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Article
Open AccessEffect of a CGMS and SMBG on Maternal and Neonatal Outcomes in Gestational Diabetes Mellitus: a Randomized Controlled Trial
In this study, we sought to investigate the effects of a continuous glucose monitoring system (CGMS) on maternal and neonatal outcomes. A total of 106 women with gestational diabetes mellitus (GDM) in gestatio...
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Article
Open AccessAnticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways
High levels of thymidine kinase 1 (TK1) and thymidine phosphorylase (TYMP) are key molecular targets by thymidine therapeutics in cancer treatment. The dual roles of TYMP as a tumor growth factor and a key act...
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Article
Mass production of highly monodisperse polymeric nanoparticles by parallel flow focusing system
Nanoparticles can be prepared through nanoprecipitation by mixing polymers dissolved in organic solvents with anti-solvents. However, due to the inability to precisely control the mixing processes during the s...
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Article
Open AccessGrowth and Formation Mechanism of Branched Carbon Nanotubes by Pyrolysis of Iron(II) Phthalocyanine
In this letter, a route for synthesizing vertically aligned multi-walled carbon nanotubes (MWCNTs) with branched nanotubes in large area was reported. The branched MWCNTs up to about 30% can be generated by th...
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Article
Luminescent properties and the morphology of SrMoO4:Eu3+ powders synthesized via combining sol-gel and solid-state route
SrMoO4:Eu3+ red phosphors were prepared by combining sol-gel and solid-state route. Citric acid and ethylenediaminetetraacetic acid (EDTA), employed as the chelating agents, were added to the aqueous solutions of...
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Article
Genome duplication effects on pollen development and the interrelated physiological substances in tetraploid rice with polyploid meiosis stability
The breeding of polyploid rice made no breakthrough for a long time because of low seed set. The discovery and application of polyploid meiosis stability (PMeS) material played a pivotal role in solving this p...
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Article
ɛ-inclusion: privacy preserving re-publication of dynamic datasets
This paper presents a novel privacy principle, ɛ-inclusion, for re-publishing sensitive dynamic datasets. ɛ-inclusion releases all the quasi-identifier values directly and uses permutation-based method and substi...