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    Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

    Combination of CDK4/6 inhibitors and endocrine therapy improves clinical outcome in advanced oestrogen receptor (ER)-positive breast cancer, however relapse is inevitable. Here, we show in model systems that o...

    Sunil Pancholi, Ricardo Ribas, Nikiana Simigdala, Eugene Schuster… in Oncogene (2020)

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