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Article
Open AccessUmbilical mesenchymal stem cell-derived extracellular vesicles as enzyme delivery vehicle to treat Morquio A fibroblasts
Mucopolysaccharidosis IVA (Morquio A syndrome) is a lysosomal storage disease caused by the deficiency of enzyme N-acetylgalactosamine-6-sulfate sulfatase (GALNS), which results in the accumulation of the glycosa...
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Article
Effect of size on the cellular endocytosis and controlled release of mesoporous silica nanoparticles for intracellular delivery
Due to the unique physicochemical properties and membrane-permeable capacity, mesoporous silica nanoparticles (MSNs) are considered as an ideal carrier for intracellular delivery. Herein, we endeavored to addr...
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Article
The bio-functional role of calcium in mesoporous silica xerogels on the responses of osteoblasts in vitro
Mesoporous silica xerogels with various amount of calcium (0, 5, 10 and 15%, named m-SXC0, m-SXC5, m-SXC10 and m-SXC15, respectively) were synthesized by template sol–gel methods, and cell responses to m-SXCs ...