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  1. Article

    Open Access

    lncRNA-SOX2OT promotes hepatocellular carcinoma invasion and metastasis through miR-122-5p-mediated activation of PKM2

    Tumor cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect, but the involvement of Warburg effect in liver cancer cell metastasis is not well understood. I...

    Yingjian Liang, Dandan Zhang, Tongsen Zheng, Guangchao Yang, Jiabei Wang… in Oncogenesis (2020)

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  2. Article

    Haplotype-Based Case-Control Study of the Association between the Guanylate Cyclase Activator 2B (GUCA2B, Uroguanylin) Gene and Essential Hypertension

    Uroguanylin (gene name: guanylate cyclase activator 2B, GUCA2B) is a peptide regulator of intestinal salt and water transport. It has been reported that the uroguanylin knockout mouse exhibits elevated blood p...

    Yukie Yoshikawa, Tomohiro Nakayama, Kosuke Saito, Peng Hui… in Hypertension Research (2007)

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  3. Article

    Common Single Nucleotide Polymorphisms in Japanese Patients with Essential Hypertension: Aldehyde Dehydrogenase 2 Gene as a Risk Factor Independent of Alcohol Consumption

    Essential hypertension (EH) is a multifactorial disorder determined by the interaction of environmental and genetic factors. EH patients' responses to these factors may vary, depending on differences in their ...

    Peng Hui, Tomohiro Nakayama, Akihiko Morita, Naoyuki Sato… in Hypertension Research (2007)

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