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  1. Article

    Open Access

    Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying

    Hair conditions, such as hair loss and graying, are prevalent human conditions. But they are often poorly controlled due to our insufficient understanding of human scalp hair follicle (hsHF) in health and dise...

    Sijie Wu, Yao Yu, Caiyue Liu, **a Zhang, Peiying Zhu, You Peng, **nyu Yan… in Cell Discovery (2022)

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    Article

    A stress-induced miR-31–CLOCK–ERK pathway is a key driver and therapeutic target for skin aging

    Regressive changes in epithelial stem cells underlie mammalian skin aging, but the driving mechanisms are not well understood. Here, we report that mouse skin hair follicle stem cell (HFSC) aging is initiated ...

    Yao Yu, **a Zhang, Fengzhen Liu, Peiying Zhu, Li** Zhang, You Peng… in Nature Aging (2021)