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Article
Open AccessDifferential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern
The current COVID-19 vaccines protect against severe disease, but are not effective in controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical models of severe and mo...
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Article
Cross-talk between lung cancer and bones results in neutrophils that promote tumor progression
Lung cancer is the leading cause of cancer mortality around the world. The lack of detailed understanding of the cellular and molecular mechanisms participating in the lung tumor progression restrains the deve...
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Article
Targeting glioblastoma-derived pericytes improves chemotherapeutic outcome
Glioblastoma is the most common malignant brain cancer in adults, with poor prognosis. The blood–brain barrier limits the arrival of several promising anti-glioblastoma drugs, and restricts the design of effic...
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Article
Macrophages Generate Pericytes in the Develo** Brain
Pericytes are defined by their anatomical location encircling blood vessels' walls with their long projections. The exact embryonic sources of cerebral pericytes remain poorly understood, especially because of...