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  1. No Access

    Article

    Relationship of Bone Mineralization Density Distribution (BMDD) in Cortical and Cancellous Bone Within the Iliac Crest of Healthy Premenopausal Women

    Bone mineralization density distribution (BMDD) is an important determinant of bone mechanical properties. The most available skeletal site for access to the BMDD is the iliac crest. Compared to cancellous bo...

    B. M. Misof, D. W. Dempster, Hua Zhou, P. Roschger… in Calcified Tissue International (2014)

  2. Article

    Open Access

    Osteoclasts on Bone and Dentin In Vitro: Mechanism of Trail Formation and Comparison of Resorption Behavior

    The main function of osteoclasts in vivo is the resorption of bone matrix, leaving behind typical resorption traces consisting of pits and trails. The mechanism of pit formation is well described, but less is ...

    M. Rumpler, T. Würger, P. Roschger, E. Zwettler… in Calcified Tissue International (2013)

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  3. Article

    Open Access

    Combination of Nanoindentation and Quantitative Backscattered Electron Imaging Revealed Altered Bone Material Properties Associated with Femoral Neck Fragility

    Osteoporotic fragility fractures were hypothesized to be related to changes in bone material properties and not solely to reduction in bone mass. We studied cortical bone from the superior and inferior sectors...

    N. Fratzl-Zelman, P. Roschger, A. Gourrier, M. Weber… in Calcified Tissue International (2009)

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  4. Article

    Open Access

    New Suggestions for the Mechanical Control of Bone Remodeling

    Bone is constantly renewed over our lifetime through the process of bone (re)modeling. This process is important for bone to allow it to adapt to its mechanical environment and to repair damage from everyday l...

    J. W. C. Dunlop, M. A. Hartmann, Y. J. Bréchet, P. Fratzl… in Calcified Tissue International (2009)

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  5. No Access

    Article

    Complementary Information on In Vitro Conversion of Amorphous (Precursor) Calcium Phosphate to Hydroxyapatite from Raman Microspectroscopy and Wide-Angle X-Ray Scattering

    In addition to mechanical functions, bones have an essential role in metabolic activity as mineral reservoirs that are able to absorb and release ions. Bioapatite, considered the major component in the mineral...

    M. Kazanci, P. Fratzl, K. Klaushofer, E. P. Paschalis in Calcified Tissue International (2006)

  6. No Access

    Article

    Association of COLIA1 Sp1 Alleles with Defective Bone Nodule Formation In Vitro and Abnormal Bone Mineralization In Vivo

    Previous work identified a G/T polymorphism affecting a Sp1 binding site in a regulatory region of the COLIA1 gene that predisposes to osteoporotic fractures by affecting bone strength through mechanisms that are...

    T. L. Stewart, P. Roschger, B. M. Misof, V. Mann… in Calcified Tissue International (2005)

  7. No Access

    Article

    Targeted Overexpression of Vitamin D Receptor in Osteoblasts Increases Calcium Concentration Without Affecting Structural Properties of Bone Mineral Crystals

    Increased cross-sectional area and strength of long bones has been observed in transgenic mice with 2-fold (OSV9) and 3-fold (OSV3) elevation of osteoblast vitamin D receptor (VDR) levels. In the present study...

    B. M. Misof, P. Roschger, W. Tesch, P. A. Baldock… in Calcified Tissue International (2003)

  8. No Access

    Article

    Mineralized Microstructure of Calcified Avian Tendons: A Scanning Small Angle X-ray Scattering Study

    The micrometer level spatial distribution of the size, shape, and orientation of mineral crystallites in the calcifying matrix of tendons near the edge of the mineralizing front was investigated by scanning sm...

    H. S. Gupta, P. Roschger, I. Zizak, N. Fratzl-Zelman… in Calcified Tissue International (2003)

  9. No Access

    Article

    Graded Microstructure and Mechanical Properties of Human Crown Dentin

    W. Tesch, N. Eidelman, P. Roschger, F. Goldenberg… in Calcified Tissue International (2001)

  10. No Access

    Article

    Scanning Small Angle X-ray Scattering Analysis of Human Bone Sections

    Scanning small-angle X-ray scattering (scanning SAXS) was applied for the first time on bone to compare results from SAXS directly with those from other position-sensitive methods, such as light and polarized...

    S. Rinnerthaler, P. Roschger, H. F. Jakob, A. Nader… in Calcified Tissue International (1999)

  11. No Access

    Article

    Characterization of bone mineral crystals in horse radius by small-angle X-ray scattering

    The size and the orientation of the bone salt (mineral) crystals in the cranial and caudal zones in the transverse midshaft section of the equine radius were investigated by small-angle X-ray scattering (SAXS)...

    P. Fratzl, S. Schreiber, A. Boyde in Calcified Tissue International (1996)