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  1. No Access

    Article

    The Binding of Semax, ACTH 4–10 Heptapeptide, to Plasma Membranes of the Rat Forebrain Basal Nuclei and Its Biodegradation

    The binding characteristics of the peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro) to plasma membranes of basal nuclei of the rat forebrain and the dynamics of its degradation during its incubation with these memb...

    O. V. Dolotov, Yu. A. Zolotarev, E. M. Dorokhova… in Russian Journal of Bioorganic Chemistry (2004)

  2. No Access

    Article

    Evenly tritium labeled peptides in study of peptide in vivo and in vitro biodegradation

    Biologically active peptides evenly labeled with tritium were used for studying the in vitro and in vivo biodegradation of the peptides. Tritium-labeled peptides with a specific radioactivity of 50–150 Ci/mmol...

    Yu. A. Zolotarev, A. K. Dadayan, O. V. Dolotov… in Russian Journal of Bioorganic Chemistry (2006)

  3. No Access

    Article

    Degradation of the ACTH(4-10) analog Semax in the presence of rat basal forebrain cell cultures and plasma membranes

    Here a new approach of the elucidation of paths of proteolytic biodegradation of physiologically active peptides, based on the use of a peptide with isotopic label at all amino acid residues and the enrichment...

    Yu. A. Zolotarev, O. V. Dolotov, L. S. Inozemtseva, A. K. Dadayan… in Amino Acids (2006)