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  1. Article

    Open Access

    SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

    Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant challenges for contemporary biological assays....

    Michael C Ryan, Barry R Zeeberg, Natasha J Caplen, James A Cleland in BMC Bioinformatics (2008)