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  1. No Access

    Article

    Immunological Efficacy and Safety of Synthesized CpG Oligodeoxynucleotides

    The technology for synthesis is described, and the adjuvant properties of CpG oligodeoxynucleotides (CpG-ODNs) are assessed. CpG-ODN sequences were generated according to the available sequences on an automati...

    O. M. Kudriavtseva, A. P. Semakova, N. I. Mikshis… in Applied Biochemistry and Microbiology (2018)

  2. Article

    Effect of Antigens Obtained from the Recombinant Strain Bacillus anthracis 55ΔTPA-1Spo– on Organs and Tissues of Immunized Animals

    The recombinant B. anthracis strain 55ΔTPA-1Spo– was used for the development and trial of a method for the simultaneous production of immunogenic anthrax antigens, a protective antigen, and the EA1 protein of th...

    N. I. Mikshis, P. Yu. Popova, A. P. Semakova… in Applied Biochemistry and Microbiology (2018)

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    Article

    Asporogenic recombinant producer of anthrax protective antigen

    An asporogenic recombinant strain Bacillus anthracis 55ΔTPA-1(Spo−) producing anthrax protective antigen (PA) was obtained. The strain contains structural gene pag as a part of a hybrid replicon pUB110PA-1 and la...

    N. I. Mikshis, O. M. Kudryavtseva, D. V. Shulepov… in Applied Biochemistry and Microbiology (2011)