3 Result(s)
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Article
Open AccessDevelopment and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA)
Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methyla...
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Article
FACT mediates cohesin function on chromatin
Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here, we ...
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Article
Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development
Cell competition is emerging as a quality-control mechanism that eliminates unfit cells in a wide range of settings from development to the adult. However, the nature of the cells normally eliminated by cell c...
