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Article

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma

Loss of function of the von Hippel-Lindau (VHL) tumor suppressor gene is a hallmark of clear cell renal cell carcinoma (ccRCC). The importance of heterogeneity in the loss of this tumor suppressor has been und...

Junhui Hu, ** Tan, Moe Ishihara… in Signal Transduction and Targeted Therapy (2023)