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  1. No Access

    Article

    Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice

    Urolithin A (UroA), a dietary phytochemical, is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins (ETs). The efficiency of ETs metabolism to UroA in humans depends on gut microbiot...

    Meng-yun Xu, **g-**g Xu, Li-**g Kang, Zheng-hong Liu in Acta Pharmacologica Sinica (2024)

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    Article

    Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers in the world. The therapeutic outlook for HCC patients has significantly improved with the advent and development of systematic and t...

    Fan Yang, Lin Jia, Hong-chao Zhou, **g-nan Huang in Acta Pharmacologica Sinica (2024)

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    Article

    Up-regulation of microglial chemokine CXCL12 in anterior cingulate cortex mediates neuropathic pain in diabetic mice

    Diabetic patients frequently experience neuropathic pain, which currently lacks effective treatments. The mechanisms underlying diabetic neuropathic pain remain unclear. The anterior cingulate cortex (ACC) is ...

    Zi-hua Song, **ang-Jie Song, Chen-ling Yang, Peng Cao, Yu Mao in Acta Pharmacologica Sinica (2023)

  4. Article

    Open Access

    The facilitating role of phycospheric heterotrophic bacteria in cyanobacterial phosphonate availability and Microcystis bloom maintenance

    Phosphonates are the main components in the global phosphorus redox cycle. Little is known about phosphonate metabolism in freshwater ecosystems, although rapid consumption of phosphonates has been observed fr...

    Liang Zhao, Li-Zhou Lin, Ying Zeng, Wen-Kai Teng, Meng-Yun Chen in Microbiome (2023)

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    Article

    The neural dynamics associated with lexicality effect in reading single Chinese words, pseudo-words and non-words

    In previous word reading studies, lexicality has been used as a variable to examine the impacts of word form and meaning information on the many stages of word recognition process. Yet the neural dynamics asso...

    Fei Gao, Jianqin Wang, Chenggang Wu, Meng-yun Wang, Juan Zhang in Cognitive Neurodynamics (2022)

  6. Article

    Open Access

    Impact of cumulative cisplatin dose in childhood nasopharyngeal carcinoma based on neoadjuvant chemotherapy response in the intensity-modulated radiotherapy era: a real-world study

    We aimed to comprehensively investigate the optimal cumulative cisplatin dose during concurrent chemoradiotherapy (CC-CCD) for locoregionally advanced nasopharyngeal carcinoma (CA-LANPC) with different tumor r...

    Ya-Nan **, Meng-Yun Qiang, Meng-Meng Liu, Zhi-Bin Cheng in Cancer Cell International (2021)

  7. Article

    Open Access

    Early postnatal irradiation‐induced age‐dependent changes in adult mouse brain: MRI based characterization

    Brain radiation exposure, in particular, radiotherapy, can induce cognitive impairment in patients, with significant effects persisting for the rest of their life. However, the main mechanisms leading to this ...

    Bo Xu Ren, Isaac Huen, Zi Jun Wu, Hong Wang, Meng Yun Duan in BMC Neuroscience (2021)

  8. Article

    Open Access

    Secondary donor-derived humanized CD19-modified CAR-T cells induce remission in relapsed/refractory mixed phenotype acute leukemia after allogeneic hematopoietic stem cell transplantation: a case report

    Mixed phenotype acute leukemia (MPAL) is a rare leukemia and is regarded as a high-risk entity with a poor prognosis. Induction therapy of an acute lymphoblastic leukemia type or hybrid regimen and hematopoiet...

    Meng-Yun Li, Zhi-Hong Lin, Ming-Ming Hu, Li-Qing Kang, **ao-xia Wu in Biomarker Research (2020)

  9. Article

    Retraction Note to: Effects of dietary glycerol monolaurate on productive performance, egg quality, serum biochemical indices, and intestinal morphology of laying hens

    The authors have retracted this article (Zhao et al., 2019) due to significant overlap with a previously published Chinese language article (Liu et al., 2017), including overlap in Table 1, Table 2, Table 3, T...

    Min-jie Zhao, Hai-ying Cai, Meng-yun Liu in Journal of Zhejiang University-SCIENCE B (2020)

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    Article

    RETRACTED ARTICLE: Effects of dietary glycerol monolaurate on productive performance, egg quality, serum biochemical indices, and intestinal morphology of laying hens

    Glycerol monolaurate (GML) has been widely used as an effective antibacterial emulsifier in the food industry. A total of 360 44-week-old Hy-Line brown laying hens were randomly distributed into four groups ea...

    Min-jie Zhao, Hai-ying Cai, Meng-yun Liu in Journal of Zhejiang University-SCIENCE B (2019)

  11. Article

    Open Access

    Serum GP73 predicts posthepatectomy outcomes in patients with hepatocellular carcinoma

    Serum GP73 is a useful biomarker in assessing hepatic fibrosis degree. The aim of this study was to evaluate the predictive value of serum GP73 level for posthepatectomy short-term outcomes in hepatocellular c...

    Meng-yun Ke, **ao-ning Wu, Yao Zhang, Saisai Wang in Journal of Translational Medicine (2019)

  12. Article

    Open Access

    Survival and prognostic factors of non-small cell lung cancer patients with postoperative locoregional recurrence treated with radical radiotherapy

    Locoregional recurrence remains the challenge for long-term survival of non-small cell lung cancer (NSCLC) patients after radical surgery, and curative-intent radiotherapy could be a treatment choice. This stu...

    Li Ma, Bo Qiu, Jun Zhang, Qi-Wen Li, Bin Wang, Xu-Hui Zhang in Chinese Journal of Cancer (2017)

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    Article

    Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women

    The kinesin-like factor 1 B (KIF1B) gene plays an important role in the process of apoptosis and the transformation and progression of malignant cells. Genetic variations in KIF1B may contribute to risk of epithe...

    Ting-Yan Shi, Zhi Jiang, Rong Jiang, Sheng Yin, Meng-Yun Wang, Ke-Da Yu in Tumor Biology (2015)

  14. Article

    Molecular identification and interaction assay of the gene (OsUbc13) encoding a ubiquitin-conjugating enzyme in rice

    The ubiquitin (Ub)-conjugating enzyme, Ubc13, has been known to be involved in error-free DNA damage tolerance (or post-replication repair) via catalyzing Lys63-linked polyubiquitin chains formation together w...

    Ya Wang, Meng-yun Xu, Jian-** Liu in Journal of Zhejiang University-SCIENCE B (2014)

  15. No Access

    Article

    Polymorphisms of the Interleukin 6 gene contribute to cervical cancer susceptibility in Eastern Chinese women

    Interleukin 6 (IL6) encodes a cytokine protein, which functions in inflammation, maintains immune homeostasis and plays important roles in cervical carcinogenesis. Single nucleotide polymorphisms (SNPs) in IL6 th...

    Ting-Yan Shi, Mei-Ling Zhu, **g He, Meng-Yun Wang, Qiao-**n Li in Human Genetics (2013)

  16. Article

    Open Access

    A pri-miR-218variant and risk of cervical carcinoma in Chinese women

    MicroRNA (miRNA)-related single nucleotide polymorphisms (SNPs) may compromise miRNA binding affinity and modify mRNA expression levels of the target genes, thus leading to cancer susceptibility. However, few ...

    Ting-Yan Shi, **ao-Jun Chen, Mei-Ling Zhu, Meng-Yun Wang, **g He, Ke-Da Yu in BMC Cancer (2013)

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    Article

    Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations

    DNA repair genes play an important role in maintaining stability and integrity of genomic DNA. Polymorphisms in nucleotide excision repair genes may cause variations in DNA repair capacity phenotype and thus c...

    **g He, Li-**n Qiu, Meng-Yun Wang, Rui-** Hua, Ruo-**n Zhang in Human Genetics (2012)

  18. Article

    Open Access

    Oxidized Low-Density Lipoprotein-Dependent Platelet-Derived Microvesicles Trigger Procoagulant Effects and Amplify Oxidative Stress

    The fundamental mechanisms that underlie platelet activation in atherothrombosis are still obscure. Oxidative stress is involved in central features of atherosclerosis. Platelet-derived microvesicles (PMVs) co...

    Hua Wang, Zhi-Hao Wang, **g Kong, Meng-Yun Yang, Gui-Hua Jiang in Molecular Medicine (2012)