7 Result(s)
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Article
Mehrdad Hamidi
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Article
Enhanced Antitumor and Antimetastatic Activity of pH-Responsive Curcumin-Loaded Chitosan-Selenium Nanocomposites against Breast Cancer
Due to low toxicity and anti-cancer activity, selenium nanoparticles have been studied to treat various cancers. In the present study, curcumin-loaded selenium-chitosan nanocomposites (CUR-Cs-SeNCs) were prepa...
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Chitosan conjugated-ordered mesoporous silica: a biocompatible dissolution enhancer for promoting the antidiabetic effect of a poorly water-soluble drug of repaglinide
The oral pathway is the preferred drug administration route in pharmaceutical sciences, however, the most employed ‘highly active’ drug candidates suffer from poor water solubility. The aim of this study was t...
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Article
Magnetic molecularly imprinted polymer nanoparticles for dispersive micro solid-phase extraction and determination of buprenorphine in human urine samples by HPLC-FL
A simple, sensitive and accessible while reliable method was developed and validated for quantitation of buprenorphine (Bup) as a highly lipophilic drug in human urine samples. The proposed method is based on ...
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Article
Open AccessRepaglinide-loaded solid lipid nanoparticles: effect of using different surfactants/stabilizers on physicochemical properties of nanoparticles
Repaglinide is an efficient anti-diabetic drug which is prescribed widely as multi-dosage oral daily regimens. Due to the low compliance inherent to each multi-dosage regimen, development of prolonged-release ...
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Article
Open AccessThe impact of polymer coatings on magnetite nanoparticles performance as MRI contrast agents: a comparative study
Superparamagnetic iron oxide nanoparticles (SPIONs) are the most commonly used negative MRI contrast agent which affect the transverse (T2) relaxation time. The aim of the present study was to investigate the imp...
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Article
Open AccessArtemia salina as a model organism in toxicity assessment of nanoparticles
Because of expanding presence of nanomaterials, there has been an increase in the exposure of humans to nanoparticles that is why nanotoxicology studies are important. A number of studies on the effects of nan...
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A Rapid and Sensitive LC–MS Method for Determination of Ezetimibe Concentration in Human Plasma: Application to a Bioequivalence Study
A selective and highly sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been developed for determination of ezetimibe concentrations in human plasma. Ezetim...
