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  1. Article

    Open Access

    A randomized phase II presurgical trial of weekly low-dose tamoxifen versus raloxifene versus placebo in premenopausal women with estrogen receptor-positive breast cancer

    We previously demonstrated that 1 or 5 mg per day of tamoxifen (T) given for four weeks before surgery reduces Ki-67 in breast cancer (BC) patients to the same extent as the standard 20 mg/d. Given the long ha...

    Davide Serrano, Matteo Lazzeroni, Sara Gandini, Debora Macis… in Breast Cancer Research (2013)

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  2. Article

    Open Access

    Breast ductal lavage for biomarker assessment in high risk women: rationale, design and methodology of a randomized phase II clinical trial with nimesulide, simvastatin and placebo

    Despite positive results from large phase III clinical trials proved that it is possible to prevent estrogen-responsive breast cancers with selective estrogen receptor modulators and aromatase inhibitors, no s...

    Matteo Lazzeroni, Aliana Guerrieri-Gonzaga, Davide Serrano… in BMC Cancer (2012)

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  3. No Access

    Article

    Breast Cancer Prevention Trials Using Retinoids

    Retinoids have been studied as chemopreventive agents in clinical trials. Given their ability to inhibit mammary carcinogenesis in preclinical models. Fenretinide has extensively been investigated because of i...

    Andrea Decensi, Davide Serrano… in Journal of Mammary Gland Biology and Neopl… (2003)