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  1. Article

    Open Access

    Survey of oxaliplatin-associated neurotoxicity using an interview-based questionnaire in patients with metastatic colorectal cancer

    New chemotherapy regimens for patients with colorectal cancer have improved survival, but at the cost of clinical toxicity. Oxaliplatin, an agent used in first-line therapy for metastatic colorectal cancer, ca...

    Gregory D Leonard, Maurice A Wright, Mary G Quinn, Suzanne Fioravanti… in BMC Cancer (2005)

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    Article

    A phase I and pharmacologic study of weekly gemcitabine in combination with infusional 5-fluorodeoxyuridine and oral calcium leucovorin

    Since preclinical studies have shown more than additive cytotoxicity and DNA damage with the combination of gemcitabine and 5-fluoro-2′-deoxyuridine (FUDR), we studied this combination in a phase I trial.

    Jean L. Grem, Mary G. Quinn, Bruce Keith… in Cancer Chemotherapy and Pharmacology (2003)

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    Article

    Pharmacokinetic and pharmacodynamic effects of oral eniluracil, fluorouracil and leucovorin given on a weekly schedule

    To determine the toxicities and pharmacokinetic effects of eniluracil (EU) given on two weekly dosing schedules with 5-fluorouracil (5-FU) and leucovorin (LV).

    **ao-Du Guo, Nancy Harold, M. Wasif Saif… in Cancer Chemotherapy and Pharmacology (2003)