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Effect of chemogenetic actuator drugs on prefrontal cortex-dependent working memory in nonhuman primates

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  1. Article

    Open Access

    Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

    Neuronal circuits within the prefrontal cortex (PFC) mediate higher cognitive functions and emotional regulation that are disrupted in psychiatric disorders. The PFC undergoes significant maturation during ado...

    Michael L. Miller, Benjamin Chadwick, Dara L. Dickstein… in Molecular Psychiatry (2019)

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  2. Article

    Chemogenetic Inactivation of Dorsal Anterior Cingulate Cortex Neurons Disrupts Attentional Behavior in Mouse

    Attention is disrupted commonly in psychiatric disorders, yet mechanistic insight remains limited. Deficits in this function are associated with dorsal anterior cingulate cortex (dACC) excitotoxic lesions and ...

    Hiroyuki Koike, Michael P Demars, Jennifer A Short… in Neuropsychopharmacology (2016)

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