3 Result(s)
within
Article
Mark Callaghan
-
Article
Open AccessModifiable risk factors for post-operative delirium in older adults undergoing major non-cardiac elective surgery: a multi-centre, trainee delivered observational cohort feasibility study and trainee survey
Post-operative delirium (POD) is an acute brain failure which may occur following major surgery, with serious implications for participants and caregivers. Evidence regarding optimal anaesthetic management for...
-
Article
Open AccessDual-barcoded shotgun expression library sequencing for high-throughput characterization of functional traits in bacteria
A major challenge in genomics is the knowledge gap between sequence and its encoded function. Gain-of-function methods based on gene overexpression are attractive avenues for phenotype-based functional screens...
-
Article
Mutant phenotypes for thousands of bacterial genes of unknown function
One-third of all protein-coding genes from bacterial genomes cannot be annotated with a function. Here, to investigate the functions of these genes, we present genome-wide mutant fitness data from 32 diverse b...
