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Article
Open AccessElectrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors
Polyamines have fundamental roles in brain homeostasis as key modulators of cellular excitability. Several studies have suggested alterations in polyamine metabolism in stress related disorders, suicide, depre...
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Article
Erratum: Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
Correction to: Translational Psychiatry (2015) 5, e636; doi:10.1038/tp.2015.134; published online 15 September 2015 In the Acknowledgments section, the funding through The Brain & Behavior Research Foundation ...
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Article
Open AccessA genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder
Elevated cerebrospinal fluid (CSF) levels of the glia-derived N-methyl-D-aspartic acid receptor antagonist kynurenic acid (KYNA) have consistently been implicated in schizophrenia and bipolar disorder. Here, we c...
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Article
Open AccessVariable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder
Stress can be a predisposing factor to psychiatric disorders and has been associated with decreased neurogenesis and reduced hippocampal volume especially in depression. Similarly, in white blood cells chronic...