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Adaptation of the ubiquitin-proteasome proteolytic pathway in cancer cachexia

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  1. Article

    Open Access

    Specific shifts in the endocannabinoid system in hibernating brown bears

    In small hibernators, global downregulation of the endocannabinoid system (ECS), which is involved in modulating neuronal signaling, feeding behavior, energy metabolism, and circannual rhythms, has been report...

    Christian Boyer, Laura Cussonneau, Charlotte Brun, Christiane Deval in Frontiers in Zoology (2020)

  2. Article

    Open Access

    Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice

    Physical activity is known as an effective strategy for prevention and treatment of Type 2 Diabetes. The aim of this work was to compare the effects of a traditional Moderate Intensity Continuous Training (MIC...

    Vivien Chavanelle, Nathalie Boisseau, Yolanda F Otero, Lydie Combaret in Scientific Reports (2017)

  3. Article

    Open Access

    Proteomics of muscle chronological ageing in post-menopausal women

    Muscle ageing contributes to both loss of functional autonomy and increased morbidity. Muscle atrophy accelerates after 50 years of age, but the mechanisms involved are complex and likely result from the alter...

    Marine Gueugneau, Cécile Coudy-Gandilhon, Ophélie Gourbeyre in BMC Genomics (2014)

  4. Article

    Open Access

    Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm

    Controlled mechanical ventilation (CMV) induces profound modifications of diaphragm protein metabolism, including muscle atrophy and severe ventilator-induced diaphragmatic dysfunction. Diaphragmatic modificat...

    Emmanuel Futier, Jean-Michel Constantin, Lydie Combaret, Laurent Mosoni in Critical Care (2008)