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Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury

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  1. Article

    Tissue-specific alterations in expression and function of P-glycoprotein in streptozotocin-induced diabetic rats

    To investigate the changes of expression and function of P-glycoprotein (P-GP) in cerebral cortex, hippocampus, liver, intestinal mucosa and kidney of streptozocin-induced diabetic rats.

    Lu-lu Zhang, Liang Lu, Shi **, **n-yue **g, Dan Yao, Nan Hu… in Acta Pharmacologica Sinica (2011)

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  2. Article

    Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays

    Synthetic glucocorticoids (GCs) have been widely used in the treatment of a broad range of inflammatory diseases, but their clinic use is limited by undesired side effects such as metabolic disorders, osteopor...

    **-** Pang, Xue-** Hu, Yun-xia Wang, Jia-ning Liao… in Acta Pharmacologica Sinica (2022)

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  3. Article

    Open Access

    Targeted demethylation at ZNF154 promotor upregulates ZNF154 expression and inhibits the proliferation and migration of Esophageal Squamous Carcinoma cells

    Zinc finger protein 154 (ZNF154) is hypermethylated at the promoter in many epithelial-derived solid tumors. However, its methylation status and function in esophageal squamous carcinoma (ESCC) are poorly unde...

    Wenting He, Shiyong Lin, Yi Guo, Yuanzhong Wu, Lu-Lu Zhang, Qiling Deng… in Oncogene (2022)

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  4. Article

    Open Access

    Risk Factors for Glycemic Control in Hospitalized Patients with Type 2 Diabetes Receiving Continuous Subcutaneous Insulin Infusion Therapy

    Patients with diabetes are confronted with numerous obstacles to achieve adequate glycemic control during hospitalization. The aim of this study was to explore the risk factors associated with glycemic control...

    Shun-hua Wang, Wei Shao, Qiu-hui Jiang, Xuan-ling Zheng, Qing-bao Shen… in Diabetes Therapy (2023)

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