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Sapidolide A alleviates acetaminophen-induced acute liver injury by inhibiting NLRP3 inflammasome activation in macrophages

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  1. Article

    Open Access

    Tumor residue in patients with stage II–IVA nasopharyngeal carcinoma who received intensity-modulated radiation therapy: development and validation of a prediction nomogram integrating postradiotherapy plasma Epstein–Barr virus deoxyribonucleic acid, clinical stage, and radiotherapy dose

    To develop and validate a predictive nomogram for tumor residue 3–6 months after treatment based on postradiotherapy plasma Epstein–Barr virus (EBV) deoxyribonucleic acid (DNA), clinical stage, and radiotherap...

    Ying-Ying Huang, Jia-Yu Zhou, Ze-Jiang Zhan, Liang-Ru Ke, Wei-**ong **a in BMC Cancer (2023)

  2. Article

    Open Access

    Cisplatin-based concurrent chemoradiotherapy improved the survival of locoregionally advanced nasopharyngeal carcinoma after induction chemotherapy by reducing early treatment failure

    The aims of this study focusing on Locoregionally advanced nasopharyngeal carcinoma (LANPC) were mainly two-fold: on the one hand, to establish a cut-off value to differentiate early and late failure based on ...

    **ng-Li Yang, Lu-Lu Zhang, Jia Kou, Guan-Qun Zhou, Chen-Fei Wu, Ying Sun in BMC Cancer (2022)

  3. Article

    Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays

    Synthetic glucocorticoids (GCs) have been widely used in the treatment of a broad range of inflammatory diseases, but their clinic use is limited by undesired side effects such as metabolic disorders, osteopor...

    **-** Pang, Xue-** Hu, Yun-xia Wang, Jia-ning Liao in Acta Pharmacologica Sinica (2022)

  4. Article

    Open Access

    Patient- and treatment-related risk factors associated with neck muscle spasm in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy

    To evaluate the incidence of neck muscle spasm in nasopharyngeal carcinoma (NPC) patients that received intensity-modulated radiotherapy (IMRT), and to analyse the patient- and treatment-related risk factors a...

    Lu-Lu Zhang, Guan-Qun Zhou, Zhen-Yu Qi, **ao-Jun He, Jia-**ang Li in BMC Cancer (2017)

  5. Article

    Tissue-specific alterations in expression and function of P-glycoprotein in streptozotocin-induced diabetic rats

    To investigate the changes of expression and function of P-glycoprotein (P-GP) in cerebral cortex, hippocampus, liver, intestinal mucosa and kidney of streptozocin-induced diabetic rats.

    Lu-lu Zhang, Liang Lu, Shi **, **n-yue **g, Dan Yao, Nan Hu in Acta Pharmacologica Sinica (2011)