356 Result(s)

Article

Targeting oncogene-induced cellular plasticity for tumor therapy

Cellular plasticity, the remarkable adaptability of cancer cells to survive under various stress conditions, is a fundamental hallmark that significantly contributes to treatment resistance, tumor metastasis, ...

Bin Li, Lingling Zheng, Jianhua Yang, Lianghu Qu in Advanced Biotechnology (2024)

Article

Epigenetic control of skeletal muscle atrophy

Skeletal muscular atrophy is a complex disease involving a large number of gene expression regulatory networks and various biological processes. Despite extensive research on this topic, its underlying mechani...

Wenpeng Liang, Feng Xu, Li Li, Chunlei Peng… in Cellular & Molecular Biology Letters (2024)

Article

New mechanistic understanding of osteoclast differentiation and bone resorption mediated by P2X7 receptors and PI3K-Akt-GSK3β signaling

Osteoporosis is a global health issue characterized by decreased bone mass and microstructural degradation, leading to an increased risk of fractures. This study aims to explore the molecular mechanism by whic...

Jiajia Lu, **aojian Shi, Qiang Fu, Yaguang Han… in Cellular & Molecular Biology Letters (2024)

Article

High-throughput combination assay for studying biofilm formation of uropathogenic Escherichia coli

Uropathogenic Escherichia coli, the most common cause for urinary tract infections, forms biofilm enhancing its antibiotic resistance. To assess the effects of compounds on biofilm formation of uropathogenic Esch...

M. Li, C. D. Cruz, P. Ilina, P. Tammela in Archives of Microbiology (2024)

Article

Correction: Correlations of FCGR2A 131R/H and FCGR3A 158V/F Polymorphisms with the Susceptibility of Peri-implantitis in Chinese Han Population

Peng Li, Bingzhuo Chen, Liang Zhao, Feng Yang, Zhu Zhang… in Molecular Biotechnology (2024)

Article

Correction: Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles

Xueke Li, Yi Zhong, Wuqi Zhou, Yishu Song, Wenqu Li… in Cellular & Molecular Biology Letters (2024)

Article

Analysis of the cell wall binding domain in bacteriocin-like lysin LysL from Lactococcus lactis LAC460

Wild-type Lactococcus lactis strain LAC460 secretes prophage-encoded bacteriocin-like lysin LysL, which kills some Lactococcus strains, but has no lytic effect on the producer. LysL carries two N-terminal enzymat...

Samira Mokhtari, Yanru Li, Per E. J. Saris, Timo M. Takala in Archives of Microbiology (2024)

Article

LncRNA TRPM2-AS promotes endometrial carcinoma progression and angiogenesis via targeting miR-497-5p/SPP1 axis

Anti-angiogenic therapy has become one of the effective treatment methods for tumors. Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis and angiogenesis in EC. However, the un...

Hanbo Ma, Fengyun Weng, **aowen Tong, Huaifang Li… in Cellular & Molecular Biology Letters (2024)

Article

Application of Lineage Tracing in Central Nervous System Development and Regeneration

The central nervous system (CNS) is a complicated neural network. The origin and evolution of functional neurons and glia cells remain unclear, as do the cellular alterations that occur during the course of ce...

Hao Li, Yuan Zhuang, Bin Zhang, **aojian Xu, Baiyun Liu in Molecular Biotechnology (2024)

Article

Cuproptosis in cancer: biological implications and therapeutic opportunities

Cuproptosis, a newly identified copper (Cu)-dependent form of cell death, stands out due to its distinct mechanism that sets it apart from other known cell death pathways. The molecular underpinnings of cuprop...

Li** Li, Houfeng Zhou, Chenliang Zhang in Cellular & Molecular Biology Letters (2024)

Article

ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway

The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is expressed in the intestine, collaborates with broad neutral am...

**ze Li, Yingli Yan, Yang Fu, Zhe Chen… in Cellular & Molecular Biology Letters (2024)

Article

α-Ketoglutarate alleviates osteoarthritis by inhibiting ferroptosis via the ETV4/SLC7A11/GPX4 signaling pathway

Osteoarthritis (OA) is the most common degenerative joint disorder that causes disability in aged individuals, caused by functional and structural alterations of the knee joint. To investigate whether metaboli...

Rong He, Yuchi Wei, Zeyu Peng, Jie Yang… in Cellular & Molecular Biology Letters (2024)

Article

APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling

Alzheimer’s disease (AD) is a progressive neurodegenerative disease and apolipoprotein E (APOE) genotypes (APOE2, APOE3, and APOE4) show different AD susceptibility. Previous studies indicated that individuals...

Zhiyuan Ning, Ying Liu, Mengyao Wan, You Zuo… in Cellular & Molecular Biology Letters (2024)

Article

Acetylation modification in the regulation of macroautophagy

Macroautophagy, commonly referred to as autophagy, is an evolutionarily conserved cellular process that plays a crucial role in maintaining cellular homeostasis. It orchestrates the delivery of dysfunctional o...

Li Huang, Hongwei Guo in Advanced Biotechnology (2024)

Article

Correction to: Construction of a New Immune-Related Competing Endogenous RNA Network with Prognostic Value in Lung Adenocarcinoma

Li Liu, **g Li, Chunhui Fan, Mingyi Wen, Cunqi Li, Wen Sun… in Molecular Biotechnology (2024)

Article

ZBP1 inhibits the replication of Senecavirus A by enhancing NF-κB signaling pathway mediated antiviral response in porcine alveolar macrophage 3D4/21 cells

Senecavirus A (SVA) caused porcine idiopathic vesicular disease (PIVD) showing worldwide spread with economic losses in swine industry. Although some progress has been made on host factors regulating the repli...

Huizi Li, Tingting Zheng, Ming Chen, **aoling Lei… in Cellular & Molecular Biology Letters (2024)

Article

Lipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy

Hepatic stellate cells (HSCs) play a crucial role in the development of fibrosis in non-alcoholic fatty liver disease (NAFLD). Small extracellular vesicles (sEV) act as mediators for intercellular information ...

Shihui Li, Fuji Yang, Fang Cheng, Ling Zhu… in Cellular & Molecular Biology Letters (2024)

Article

Dysregulated dendritic cells in sepsis: functional impairment and regulated cell death

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Studies have indicated that immune dysfunction plays a central role in the pathogenesis of sepsis. D...

Li-yu Zheng, Yu Duan, Peng-yi He, Meng-yao Wu… in Cellular & Molecular Biology Letters (2024)

Article

Protective Effect of CXCR7 Against Hypoxia/Reoxygenation Injury in Renal Tubular Epithelial Cells

Acute kidney injury (AKI) is a multifactorial syndrome with complex pathophysiology and prognosis. Ischaemia‒reperfusion injury (IRI) is a major cause of induced AKI. The aim of this study was to investigate t...

** Meng, Chunli Liu, **gchun Li, ** Fang… in Cell Biochemistry and Biophysics (2024)

Article

Role of C/EBP Homologous Protein (CHOP) and Nupr1 Interaction in Endoplasmic Reticulum Stress-Induced Apoptosis of Lens Epithelial Cells

Our study mainly analyzed the mechanism of C/EBP homologous protein (CHOP) and its interacting protein Nupr1 on endoplasmic reticulum stress (ERS) induced lens epithelial cells (LEC) apoptosis. Cell proliferat...

**ghua Li, Junyi Liu, Yongying Tang, Hong Zhang, Yuan** Zhang… in Molecular Biotechnology (2024)